Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 9/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.57 |
| ▸ | RELA | Q04206 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | XBP1 | P17861 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL129182 | 0.88 | FOLH1 (0.68) | SMN1; SMN2TP53RAB9ANPC1MAPT | |
| Water SCHEMBL7811295 | 0.86 | FOLH1 (0.66) | MRGPRX4SMN1; SMN2TP53RAB9ANPC1 | |
| Isophthalic Acid SCHEMBL1557618 | 0.86 | KMT2A (0.56) | MRGPRX4SMN1; SMN2TP53PKMNFKB1 | |
| SCHEMBL3315985 | 0.85 | MRGPRX4 (0.68) | MRGPRX4SMN1; SMN2TP53PKMNFKB1 | |
| SCHEMBL25284732 | 0.82 | MRGPRX4 (0.56) | MRGPRX4SMN1; SMN2TP53PKMNFKB1 | |
| SCHEMBL27705266 | 0.81 | FOLH1 (0.59) | SMN1; SMN2TP53RAB9ANPC1MAPT | |
| Isophthalic Acid SCHEMBL21683230 | 0.81 | KMT2A (0.51) | MRGPRX4SMN1; SMN2TP53PKMNFKB1 | |
| Ether SCHEMBL10348972 | 0.81 | KMO (0.63) | MRGPRX4SMN1; SMN2TP53PKMNFKB1 | |
| SCHEMBL46935 | 0.78 | BCL2 (0.66) | MRGPRX4SMN1; SMN2TP53PKMNFKB1 | |
| Benzoic Acid SCHEMBL5085787 | 0.78 | TSHR (0.58) | SMN1; SMN2TP53RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996446-A4 | NOVEL SUBSTITUTED IMIDAZOLE COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2001-08-29 | — | — | EP | disclosed |
| EP-0996446-A1 | NOVEL SUBSTITUTED IMIDAZOLE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-05-03 | — | — | EP | disclosed |
| WO-1999001131-A1 | NOVEL SUBSTITUTED IMIDAZOLE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-01-14 | — | — | WO | disclosed |