Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.49 |
| ▸ | BCR | P11274 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.45 |
| ▸ | GLS | O94925 | 1/20 | 0.44 |
| ▸ | ATR | Q13535 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.43 |
| ▸ | IKBKG | Q9Y6K9 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12918981 | 0.90 | SMYD2 (0.56) | MAP4K4SMYD2 | |
| SCHEMBL959442 | 0.88 | GPR52 (0.53) | MAP4K4ATRHRH3IKBKBCHUK | |
| SCHEMBL12918995 | 0.87 | MAP4K4 (0.51) | MAP4K4ATRIKBKBCHUKIKBKG | |
| SCHEMBL12918983 | 0.87 | MAP4K4 (0.54) | MAP4K4SMYD2ATRIKBKBCHUK | |
| SCHEMBL12919015 | 0.86 | MAP4K4 (0.50) | ABL1BCRMAP4K4ATRHRH3 | |
| SCHEMBL12918996 | 0.86 | MAP4K4 (0.51) | MAP4K4SMYD2ATRHRH3IKBKB | |
| SCHEMBL12918997 | 0.86 | SMYD2 (0.53) | ABL1BCRMAP4K4SMYD2ATR | |
| SCHEMBL12919033 | 0.85 | MAP4K4 (0.51) | ABL1BCRMAP4K4SMYD2ATR | |
| SCHEMBL12919026 | 0.85 | MAP4K4 (0.52) | ABL1BCRMAP4K4SMYD2ATR | |
| SCHEMBL12919009 | 0.84 | MAP4K4 (0.54) | ABL1BCRMAP4K4SMYD2ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009421-A1 | COMPOUND HAVING 6-MEMBERED AROMATIC RING | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-01-13 | — | — | US | disclosed |
| US-20110009421-A1 | COMPOUND HAVING 6-MEMBERED AROMATIC RING | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009421-A1 | COMPOUND HAVING 6-MEMBERED AROMATIC RING | GPR4, NR3C2, NR5A2 | ABL1 2661/4885BCR 781/4885MAP4K4 2519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.