Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12924376 | 0.99 | MAPK14 (0.32) | RARBMAPK14MAPTTHRBBLM | |
| SCHEMBL12924284 | 0.87 | MAPK14 (0.30) | MAPK14 | |
| SCHEMBL12924378 | 0.87 | MAPK14 (0.30) | MAPK14 | |
| SCHEMBL12924328 | 0.84 | HSD17B1 (0.35) | MAPTESR1 | |
| SCHEMBL12924340 | 0.84 | HSD17B1 (0.35) | MAPTESR1 | |
| SCHEMBL12924298 | 0.81 | ESR1 (0.42) | MAPTESR1ESR2 | |
| SCHEMBL12924307 | 0.81 | ESR1 (0.42) | MAPTESR1ESR2 | |
| SCHEMBL12924299 | 0.80 | LMNA (0.40) | MAPK14MAPT | |
| SCHEMBL12924296 | 0.78 | RARB (0.39) | RARBESR1ESR2 | |
| SCHEMBL12924312 | 0.78 | RARB (0.39) | RARBESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110012098-A1 | ORGANIC TRANSISTOR | YAMAMOTO CHEMICALS, INC. (JP) | 2011-01-20 | — | — | US | disclosed |