⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28762858 | 0.98 | TSHR (0.50) | — | |
| SCHEMBL14480518 | 0.83 | ALDH1A1 (0.48) | — | |
| SCHEMBL315777 | 0.82 | ALDH1A1 (0.61) | — | |
| SCHEMBL28938347 | 0.82 | CES2 (0.42) | — | |
| SCHEMBL10578910 | 0.81 | KDM4E (0.36) | — | |
| SCHEMBL4399639 | 0.79 | — | — | |
| SCHEMBL96050 | 0.79 | — | — | |
| SCHEMBL11496511 | 0.79 | — | — | |
| SCHEMBL103388 | 0.79 | — | — | |
| SCHEMBL10337626 | 0.79 | CES2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3323 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118344695-A | Hydroxyl-enriched cycloolefin copolymer long afterglow material and application thereof | 重庆理工大学 | 2024-07-16 | — | — | CN | claimed |
| CN-117535045-B | Zn-MOF@Au NPS/DNA aptamer fluorescent probe for trace thiamethoxam detection and preparation method thereof | 中国热带农业科学院分析测试中心 | 2024-05-31 | — | — | CN | claimed |
| US-11987588-B2 | Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of heart failure and disorders related thereto | ARENA PHARMACEUTICALS, INC. (US) | 2024-05-21 | — | — | US | claimed |
| CN-117535045-A | Zn-MOF@Au NPS/DNA aptamer fluorescent probe for trace thiamethoxam detection and preparation method thereof | 中国热带农业科学院分析测试中心 | 2024-02-09 | — | — | CN | claimed |
| US-11845748-B2 | Bicyclic pyridine N-oxide derivatives useful as a factor XIa inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2023-12-19 | — | — | US | claimed |
| WO-2023168367-A1 | QUINOLINE cGAS ANTAGONIST COMPOUNDS | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2023-09-07 | — | — | WO | claimed |
| EP-4208452-A1 | QUINOLINE CGAS ANTAGONIST COMPOUNDS | Immunesensor Therapeutics, Inc. (US) | 2023-07-12 | — | — | EP | claimed |
| CN-115124474-B | Andrographolide derivative containing N heterocyclic structure and preparation method and application thereof | 郑州大学 | 2023-06-23 | — | — | CN | claimed |
| EP-3720858-B1 | MODULATORS OF THE BETA-3 ADRENERGIC RECEPTOR USEFUL FOR THE TREATMENT OR PREVENTION OF HEART FAILURE AND DISORDERS RELATED THERETO | ARENA PHARM INC (US) | 2023-06-07 | — | — | EP | claimed |
| CN-116234802-A | Quinoline CGAS antagonist compounds | 免疫传感器治疗股份有限公司 | 2023-06-06 | — | — | CN | claimed |
| EP-0122321-B1 | HYDROXYBENZYLAMINO DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | MERCK & CO. INC. (US) | 1988-08-03 | — | — | EP | claimed |
| US-4752337-A | Recording liquid for ink jet recording systems | BAYER AKTIENGESELLSCHAFT (DE) | 1988-06-21 | — | — | US | claimed |
| EP-0249127-A2 | Recording fluid for ink jet painting systems | BAYER AG (DE) | 1987-12-16 | — | — | EP | claimed |
| EP-0238061-A2 | Cephalosporin derivatives, processes for their preparation and antibacterial agents | Banyu Pharmaceutical Co., Ltd. (JP) | 1987-09-23 | — | — | EP | claimed |
| EP-0217510-A2 | Anthraquinone derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-04-08 | — | — | EP | claimed |
| EP-0103197-B1 | ACIDIC O-NITROAROMATICS AS PHOTOINHIBITORS OF POLYMERIZATION IN POSITIVE WORKING FILMS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-01-22 | — | — | EP | claimed |
| US-4461769-A | ANTIASTHEMIC AGENTS-PYRIDO(1,2-A)PYRIMIDINE COMPOUNDS | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) | 1984-07-24 | — | — | US | claimed |
| US-4091213-A | 7-Cyclizedamino-3-heterothiomethyl cephalosporin derivatives | BRISTOL-MYERS COMPANY (US) | 1978-05-23 | — | — | US | claimed |
| US-4026888-A | ANTIBIOTICS, BACTERICIDES | BRISTOL-MYERS COMPANY (US) | 1977-05-31 | — | — | US | claimed |
| US-4022804-A | ADDITION REACTION; SULFONIC ACID BROMIDES, UNSATURATED COMPOUNDS | BASF AKTIENGESELLSCHAFT (DT) | 1977-05-10 | — | — | US | claimed |