Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.53 |
| ▸ | DPP4 | P27487 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTR1E | P28566 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4610367 | 0.82 | IDO1 (0.55) | IDO1DPP4MEN1KMT2AGAA | |
| SCHEMBL16191153 | 0.80 | GAA (0.53) | IDO1MEN1KMT2AGAAL3MBTL1 | |
| SCHEMBL182619 | 0.78 | IDO1 (0.58) | IDO1DPP4MEN1KMT2AGAA | |
| SCHEMBL20721161 | 0.78 | IDO1 (0.58) | IDO1DPP4MEN1KMT2AGAA | |
| SCHEMBL2677265 | 0.78 | IDO1 (0.58) | IDO1DPP4MEN1KMT2AGAA | |
| SCHEMBL24742273 | 0.78 | IDO1 (0.58) | IDO1DPP4MEN1KMT2AGAA | |
| SCHEMBL24741625 | 0.78 | IDO1 (0.58) | IDO1DPP4MEN1KMT2AGAA | |
| SCHEMBL6387473 | 0.78 | HRH1 (0.48) | IDO1MEN1KMT2AGAAL3MBTL1 | |
| SCHEMBL30566992 | 0.77 | IDO1 (0.49) | IDO1DPP4MEN1KMT2AGAA | |
| SCHEMBL7261616 | 0.77 | MEN1 (0.47) | IDO1DPP4MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7868174-B2 | Form of a benzenesulfonamide derivative | PLIVA-ISTRAZIVANJE I RAZVOJ D.O.O. (HR) | 2011-01-11 | — | — | US | disclosed |