Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.55 |
| ▸ | DPP4 | P27487 | 2/20 | 0.50 |
| ▸ | METAP2 | P50579 | 3/20 | 0.46 |
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTR1E | P28566 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12927232 | 0.82 | IDO1 (0.53) | IDO1DPP4METAP2METAP1MEN1 | |
| SCHEMBL2769103 | 0.81 | ADRB2 (0.45) | METAP2METAP1 | |
| SCHEMBL8249190 | 0.81 | ADRB2 (0.45) | METAP2METAP1 | |
| SCHEMBL182619 | 0.79 | IDO1 (0.58) | IDO1DPP4METAP2METAP1MEN1 | |
| SCHEMBL20721161 | 0.79 | IDO1 (0.58) | IDO1DPP4METAP2METAP1MEN1 | |
| SCHEMBL24741625 | 0.79 | IDO1 (0.58) | IDO1DPP4METAP2METAP1MEN1 | |
| SCHEMBL2677265 | 0.79 | IDO1 (0.58) | IDO1DPP4METAP2METAP1MEN1 | |
| SCHEMBL24742273 | 0.79 | IDO1 (0.58) | IDO1DPP4METAP2METAP1MEN1 | |
| SCHEMBL30566992 | 0.78 | IDO1 (0.49) | IDO1DPP4METAP2METAP1MEN1 | |
| SCHEMBL8241987 | 0.78 | SLC6A3 (0.46) | METAP2OPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |