Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.49 |
| ▸ | DPP4 | P27487 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTR1E | P28566 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 3/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5680194 | 0.80 | IDO1 (0.47) | IDO1MEN1KMT2ALMNAMAPT | |
| SCHEMBL4610367 | 0.78 | IDO1 (0.55) | IDO1DPP4MEN1KMT2ALMNA | |
| SCHEMBL6704159 | 0.78 | IDO1 (0.50) | IDO1MEN1KMT2ALMNAMAPT | |
| SCHEMBL12927232 | 0.77 | IDO1 (0.53) | IDO1DPP4MEN1KMT2ALMNA | |
| SCHEMBL5372125 | 0.76 | GAA (0.49) | IDO1MEN1KMT2ALMNAMAPT | |
| SCHEMBL8705439 | 0.75 | KDM4E (0.53) | IDO1MEN1KMT2ALMNAMAPT | |
| SCHEMBL20721292 | 0.75 | IDO1 (0.55) | IDO1DPP4MEN1KMT2ALMNA | |
| SCHEMBL295253 | 0.75 | IDO1 (0.55) | IDO1DPP4MEN1KMT2ALMNA | |
| SCHEMBL2677194 | 0.75 | IDO1 (0.55) | IDO1DPP4MEN1KMT2ALMNA | |
| SCHEMBL24741625 | 0.74 | IDO1 (0.58) | IDO1DPP4MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400517-A1 | CHIRAL BIMETALLIC COOPERATIVE CATALYSIS SYSTEM AND USE THEREOF IN ASYMMETRIC SYNTHESIS OF BEDAQUILINE | SHANGHAI JIAO TONG UNIVERSITY (CN) | 2024-12-05 | — | — | US | disclosed |
| CN-116603570-A | Double-chiral metal synergistic catalytic system and application thereof in asymmetric synthesis of bedaquiline | 上海交通大学 | 2023-08-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240400517-A1 | CHIRAL BIMETALLIC COOPERATIVE CATALYSIS SYSTEM AND USE THEREOF IN ASYMMETRIC SYNTHESIS OF BEDAQUILINE | MAP2K4, MAP2K7, MAP2K5 | IDO1 1827/4885DPP4 3807/4885MEN1 2477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.