Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | HRH1 | P35367 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12933709 | 0.82 | SLC6A4 (0.72) | SLC6A4SLC6A2CYP2D6KCNH2SLC6A3 | |
| SCHEMBL2072636 | 0.82 | SLC6A4 (0.72) | SLC6A4SLC6A2CYP2D6KCNH2SLC6A3 | |
| SCHEMBL2074218 | 0.81 | SLC6A4 (1.00) | SLC6A4SLC6A2CYP2D6KCNH2SLC6A3 | |
| SCHEMBL2072655 | 0.80 | SLC6A4 (0.69) | SLC6A4SLC6A2CYP2D6KCNH2SLC6A3 | |
| SCHEMBL2075069 | 0.79 | SLC6A4 (0.67) | SLC6A4SLC6A2CYP2D6KCNH2SLC6A3 | |
| SCHEMBL13157395 | 0.78 | SLC6A4 (0.56) | SLC6A4SLC6A2CYP2D6KCNH2SLC6A3 | |
| SCHEMBL3232638 | 0.75 | SLC6A4 (0.72) | SLC6A4SLC6A2CYP2D6KCNH2SLC6A3 | |
| SCHEMBL2073934 | 0.75 | SLC6A4 (0.72) | SLC6A4SLC6A2CYP2D6KCNH2SLC6A3 | |
| SCHEMBL2074801 | 0.75 | SLC6A4 (0.72) | SLC6A4SLC6A2CYP2D6KCNH2SLC6A3 | |
| SCHEMBL13157388 | 0.74 | SLC6A4 (0.60) | SLC6A4SLC6A2CYP2D6KCNH2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7863305-B2 | 3-amino-1-arylpropyl indoles as monoamine reuptake inhibitors | ROCHE PALO ALTO LLC (US) | 2011-01-04 | — | — | US | disclosed |