Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 17/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 0.50 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14029983 | 0.77 | HRH4 (0.54) | HRH4HRH3NUDT1CHRNA7 | |
| SCHEMBL1787663 | 0.77 | HDAC1 (0.40) | HDAC1HDAC8HDAC6 | |
| SCHEMBL16844971 | 0.76 | HRH4 (0.52) | HRH4HRH3NUDT1CHRNA7 | |
| SCHEMBL9169741 | 0.76 | HRH4 (0.52) | HRH4HRH3NUDT1CHRNA7 | |
| SCHEMBL16815659 | 0.74 | MKNK1 (0.48) | HDAC1HDAC8HDAC6 | |
| SCHEMBL14561014 | 0.74 | RAB9A (0.48) | HRH4HRH3 | |
| SCHEMBL14004971 | 0.73 | HRH4 (0.50) | HRH4HRH3NUDT1CHRNA7 | |
| SCHEMBL16815597 | 0.73 | HDAC1 (0.53) | HDAC1HDAC8HDAC6 | |
| SCHEMBL12932877 | 0.73 | HRH4 (0.50) | HRH4HRH3NUDT1 | |
| SCHEMBL23554880 | 0.73 | KDM4E (0.50) | NUDT1HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7868204-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2011-01-11 | — | — | US | disclosed |