Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 15/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12919364 | 0.86 | PKM (0.36) | SMN1; SMN2NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL973525 | 0.85 | AOC3 (0.45) | AOC3SMN1; SMN2NPC1RAB9AMAOB | |
| SCHEMBL972699 | 0.80 | AOC3 (0.52) | AOC3SMN1; SMN2NPC1RAB9AMAOB | |
| Hydrochloric Acid SCHEMBL971453 | 0.79 | AOC3 (0.51) | AOC3SMN1; SMN2NPC1RAB9AMAOB | |
| SCHEMBL972997 | 0.77 | AOC3 (0.57) | AOC3SMN1; SMN2NPC1RAB9AMAOB | |
| SCHEMBL973471 | 0.77 | AOC3 (0.46) | AOC3SMN1; SMN2NPC1RAB9AMAOB | |
| SCHEMBL971534 | 0.76 | SMN1; SMN2 (0.63) | AOC3SMN1; SMN2NPC1RAB9AMAOB | |
| SCHEMBL972703 | 0.76 | AOC3 (0.62) | AOC3SMN1; SMN2NPC1RAB9AMAOB | |
| SCHEMBL15251752 | 0.75 | AOC3 (0.55) | AOC3SMN1; SMN2NPC1RAB9AMAOB | |
| SCHEMBL972194 | 0.74 | AOC3 (0.47) | AOC3SMN1; SMN2NPC1RAB9AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507690-B2 | Thiazole derivative and use thereof as VAP-1 inhibitor | R-TECH UENO, LTD. (JP) | 2013-08-13 | — | — | US | disclosed |
| US-20110015240-A1 | THIAZOLE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-TECH UENO, LTD. (JP) | 2011-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015240-A1 | THIAZOLE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | VAPB, TAS1R1, VAPA | AOC3 438/4885SMN1; SMN2 879/4885NPC1 36/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.