Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.43 |
| ▸ | ACLY | P53396 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13160674 | 0.91 | PTGDR2 (0.44) | PTGDR2ACLYPOLBPTPN1ALDH1A1 | |
| SCHEMBL12948887 | 0.87 | PTGDR2 (0.46) | PTGDR2ACLYPOLBPTPN1ALDH1A1 | |
| SCHEMBL12948774 | 0.86 | PTGDR2 (0.41) | PTGDR2ACLYPOLBPTPN1MAPT | |
| SCHEMBL990554 | 0.78 | PTGDR2 (0.53) | PTGDR2ACLYPOLBPTPN1ALDH1A1 | |
| SCHEMBL12948882 | 0.76 | PTGDR2 (0.43) | PTGDR2ACLYPOLBPTPN1MAPT | |
| SCHEMBL989200 | 0.75 | PTGDR2 (0.39) | PTGDR2ACLYPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL1949509 | 0.75 | PTGDR2 (0.54) | PTGDR2ACLYPSEN1PSEN2APH1B | |
| SCHEMBL7834622 | 0.72 | ALDH1A1 (0.59) | POLBALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL29991438 | 0.72 | ALDH1A1 (0.59) | POLBALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL13261434 | 0.71 | PTGDR2 (0.50) | PTGDR2ACLYSMN1; SMN2MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011002814-A2 | BIARYL OXYACETIC ACID COMPOUNDS | LIGAND PHARMACEUTICALS INC. (US) | 2011-01-06 | — | — | WO | disclosed |