Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | ACLY | P53396 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1077197 | 0.86 | PTGDR2 (0.41) | PTGDR2POLBARALDH1A1MAPT | |
| SCHEMBL12948887 | 0.81 | PTGDR2 (0.46) | PTGDR2PTPN1POLBALDH1A1ACLY | |
| SCHEMBL13160674 | 0.79 | PTGDR2 (0.44) | PTGDR2PTPN1POLBALDH1A1ACLY | |
| SCHEMBL1949509 | 0.78 | PTGDR2 (0.54) | PTGDR2ACLY | |
| SCHEMBL12948769 | 0.78 | PTGDR2 (0.43) | PTGDR2PTPN1POLBALDH1A1ACLY | |
| SCHEMBL1812724 | 0.78 | ALDH1A1 (0.47) | PTGDR2ALDH1A1ACLYHPGDCYP2C19 | |
| SCHEMBL987937 | 0.76 | PTGDR2 (0.43) | PTGDR2PTPN1ARALDH1A1ACLY | |
| SCHEMBL29991438 | 0.76 | ALDH1A1 (0.59) | POLBALDH1A1MAPTCYP2C9HPGD | |
| SCHEMBL7834622 | 0.76 | ALDH1A1 (0.59) | POLBALDH1A1MAPTCYP2C9HPGD | |
| SCHEMBL12147557 | 0.76 | PTGDR2 (0.54) | PTGDR2ALDH1A1ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011002814-A2 | BIARYL OXYACETIC ACID COMPOUNDS | LIGAND PHARMACEUTICALS INC. (US) | 2011-01-06 | — | — | WO | disclosed |
| WO-2011002814-A2 | BIARYL OXYACETIC ACID COMPOUNDS | LIGAND PHARMACEUTICALS INC. (US) | 2011-01-06 | — | — | WO | disclosed |