Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 6/20 | 0.43 |
| ▸ | FAP | Q12884 | 4/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.41 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8288957 | 0.90 | CCR1 (0.44) | PREPHCRTR1DRD4UTS2RDRD2 | |
| SCHEMBL12949799 | 0.88 | PREP (0.44) | PREPFAPHCRTR1DRD4UTS2R | |
| SCHEMBL14181582 | 0.87 | STAT6 (0.42) | HCRTR1DRD4UTS2RDRD2 | |
| SCHEMBL8286743 | 0.82 | PREP (0.50) | PREPFAPHCRTR1DRD4DRD2 | |
| SCHEMBL12031331 | 0.82 | CASP1 (0.42) | PREPFAPHCRTR1 | |
| SCHEMBL16281638 | 0.81 | CNR2 (0.46) | PREPFAPHCRTR1DRD4UTS2R | |
| SCHEMBL714622 | 0.80 | NPC1 (0.46) | PREP | |
| SCHEMBL12031652 | 0.80 | KMT2A (0.46) | UTS2RMBOAT4 | |
| SCHEMBL14434719 | 0.78 | ALDH1A1 (0.43) | — | |
| SCHEMBL6818900 | 0.78 | ALDH1A1 (0.50) | PREPFAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2270004-A1 | Caspase inhibitors and uses thereof | Vertex Pharmceuticals Incorporated (US) | 2011-01-05 | — | — | EP | disclosed |