Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 6/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | COMT | P21964 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.61 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.61 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12950321 | 0.90 | FTO (0.70) | FTOLMNAKMT2ACOMTMEN1 | |
| SCHEMBL12950139 | 0.90 | FTO (0.70) | FTOLMNAKMT2ACOMTMEN1 | |
| SCHEMBL12950322 | 0.88 | FTO (0.63) | FTOLMNAKMT2ACOMTMEN1 | |
| SCHEMBL5329070 | 0.87 | FTO (0.62) | FTOLMNAKMT2ACOMTMEN1 | |
| SCHEMBL5329066 | 0.87 | FTO (0.62) | FTOLMNAKMT2ACOMTMEN1 | |
| SCHEMBL12950318 | 0.87 | MEN1 (0.64) | FTOLMNAKMT2ACOMTMEN1 | |
| SCHEMBL5325767 | 0.87 | FTO (0.57) | FTOLMNAKMT2ACOMTMEN1 | |
| SCHEMBL5325763 | 0.87 | FTO (0.57) | FTOLMNAKMT2ACOMTMEN1 | |
| SCHEMBL5329471 | 0.87 | FTO (0.59) | FTOLMNAKMT2ACOMTMEN1 | |
| SCHEMBL5329487 | 0.87 | FTO (0.59) | FTOLMNAKMT2ACOMTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011008675-A2 | CATECHOLAMINE COMPOUNDS, COMPOSITIONS, AND FORMULATIONS, AND METHODS OF USING THE SAME | CHADEAYNE ANDREW R (US) | 2011-01-20 | — | — | WO | disclosed |