Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | FTO | Q9C0B1 | 5/20 | 0.64 |
| ▸ | COMT | P21964 | 4/20 | 0.64 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.64 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.64 |
| ▸ | EGFR | P00533 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12950140 | 0.90 | FTO (0.74) | MEN1KMT2AFTOCOMTABCC3 | |
| SCHEMBL12949873 | 0.90 | FTO (0.74) | MEN1KMT2AFTOCOMTABCC3 | |
| SCHEMBL12950322 | 0.89 | FTO (0.63) | MEN1KMT2AFTOCOMTABCC3 | |
| SCHEMBL5329066 | 0.88 | FTO (0.62) | MEN1KMT2AFTOCOMTABCC3 | |
| SCHEMBL5329070 | 0.88 | FTO (0.62) | MEN1KMT2AFTOCOMTABCC3 | |
| SCHEMBL12949875 | 0.87 | FTO (0.61) | MEN1KMT2AFTOCOMTABCC3 | |
| SCHEMBL12950323 | 0.87 | FTO (0.61) | MEN1KMT2AFTOCOMTABCC3 | |
| SCHEMBL4939490 | 0.87 | FTO (0.61) | MEN1KMT2AFTOCOMTABCC3 | |
| SCHEMBL12949872 | 0.87 | FTO (0.61) | MEN1KMT2AFTOCOMTABCC3 | |
| SCHEMBL5329016 | 0.87 | FTO (0.58) | MEN1KMT2AFTOCOMTABCC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011008675-A2 | CATECHOLAMINE COMPOUNDS, COMPOSITIONS, AND FORMULATIONS, AND METHODS OF USING THE SAME | CHADEAYNE ANDREW R (US) | 2011-01-20 | — | — | WO | disclosed |