Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | KCNJ11 | Q14654 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18726194 | 0.93 | NPC1 (0.33) | NPC1POLBRAB9ATDP1SMN1; SMN2 | |
| SCHEMBL12950918 | 0.90 | NPC1 (0.33) | NPC1POLBRAB9ATDP1SMN1; SMN2 | |
| SCHEMBL13516090 | 0.89 | RAB9A (0.35) | NPC1POLBRAB9ATDP1SMN1; SMN2 | |
| SCHEMBL998152 | 0.87 | NPC1 (0.33) | NPC1POLBRAB9ATDP1SMN1; SMN2 | |
| SCHEMBL13516163 | 0.86 | KCNJ11 (0.30) | KCNJ11 | |
| SCHEMBL12951218 | 0.85 | POLB (0.35) | NPC1POLBRAB9ATDP1SMN1; SMN2 | |
| SCHEMBL12950815 | 0.85 | KCNJ11 (0.37) | NPC1POLBRAB9ATDP1SMN1; SMN2 | |
| SCHEMBL13515948 | 0.85 | KCNJ11 (0.38) | KCNJ11 | |
| SCHEMBL12950901 | 0.84 | POLB (0.34) | NPC1POLBRAB9ATDP1SMN1; SMN2 | |
| SCHEMBL13515970 | 0.83 | NPC1 (0.33) | NPC1POLBRAB9ATDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011009540-A2 | PESTICIDAL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2011-01-27 | — | — | WO | disclosed |