Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 5/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.31 |
| ▸ | PDE4A | P27815 | 2/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13516056 | 0.96 | POLB (0.35) | NPC1POLBRAB9ATDP1KCNJ11 | |
| SCHEMBL13516094 | 0.94 | POLB (0.34) | NPC1POLBRAB9ATDP1KCNJ11 | |
| SCHEMBL12950918 | 0.93 | NPC1 (0.33) | NPC1POLBRAB9ATDP1KCNJ11 | |
| SCHEMBL18726194 | 0.90 | NPC1 (0.33) | NPC1POLBRAB9ATDP1KCNJ11 | |
| SCHEMBL13516049 | 0.90 | KCNJ11 (0.35) | NPC1POLBRAB9ATDP1KCNJ11 | |
| SCHEMBL13516097 | 0.90 | DRD4 (0.33) | KCNJ11 | |
| SCHEMBL12951218 | 0.89 | POLB (0.35) | NPC1POLBRAB9ATDP1KCNJ11 | |
| SCHEMBL12950901 | 0.87 | POLB (0.34) | NPC1POLBRAB9ATDP1KCNJ11 | |
| SCHEMBL999426 | 0.85 | KCNJ11 (0.37) | NPC1POLBRAB9ATDP1KCNJ11 | |
| SCHEMBL13516090 | 0.85 | RAB9A (0.35) | NPC1POLBRAB9ATDP1KCNJ11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2456759-B1 | PESTICIDAL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2017-04-19 | — | — | EP | disclosed |
| US-8822691-B2 | Pesticidal carboxamides | BAYER CROPSCIENCE AG (DE) | 2014-09-02 | — | — | US | disclosed |
| US-20120277185-A1 | Pesticidal Carboxamides | BAYER CROPSCIENDE AG (DE) | 2012-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120277185-A1 | Pesticidal Carboxamides | DDT, ACHE, AADAC | NPC1 4669/4885POLB 4507/4885RAB9A 2235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.