SCHEMBL12951069

SCHEMBL12951069

CC(C)(C)c1ccc(-c2ccc(N(c3ccc(-c4ccc(C(C)(C)C)cc4)cc3)c3ccc(N(c4ccc(N(c5ccc(-c6ccc(C(C)(C)C)cc6)cc5)c5ccc(-c6ccc(C(C)(C)C)cc6)cc5)cc4)c4ccc(N(c5ccc(-c6ccc(C(C)(C)C)cc6)cc5)c5ccc(-c6ccc(C(C)(C)C)cc6)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 4/20 0.54
TSHR P16473 1/20 0.46
LMNA P02545 2/20 0.44
TYR P14679 1/20 0.44
HTR1D P28221 1/20 0.42
ADRA1A P35348 1/20 0.42
NISCH Q9Y2I1 1/20 0.42
XDH P47989 1/20 0.42
NPC1 O15118 4/20 0.42
RAB9A P51151 4/20 0.42
PTGES O14684 1/20 0.39
ALOX5 P09917 1/20 0.39
KDM4E B2RXH2 3/20 0.38
ALDH1A1 P00352 3/20 0.37
TP53 P04637 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
MITF O75030 1/20 0.37
KMT2A Q03164 1/20 0.37
HPGD P15428 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16343998 1.00 KIF11 (0.54) KIF11TSHRLMNATYRHTR1D
SCHEMBL8642413 1.00 KIF11 (0.54) KIF11TSHRLMNATYRHTR1D
SCHEMBL14163841 0.92 TSHR (0.52) KIF11TSHRLMNATYRHTR1D
SCHEMBL13136660 0.92 TSHR (0.52) KIF11TSHRLMNATYRHTR1D
SCHEMBL6705565 0.92 TSHR (0.52) KIF11TSHRLMNATYRHTR1D
SCHEMBL17780059 0.91 KIF11 (0.47) KIF11TSHRLMNATYRHTR1D
SCHEMBL6825704 0.91 KIF11 (0.47) KIF11TSHRLMNATYRHTR1D
SCHEMBL13751266 0.91 TSHR (0.62) KIF11TSHRLMNATYRHTR1D
SCHEMBL12780902 0.91 KIF11 (0.47) KIF11TSHRLMNATYRHTR1D
SCHEMBL21392014 0.91 TSHR (0.62) KIF11TSHRLMNATYRHTR1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150129861-A1 ORGANIC MATERIAL FOR DEPOSITION, AND ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, DEPOSITION METHOD, AND MANUFACTURING METHOD FOR ORGANIC PHOTOELECTRONIC ONVERSION ELEMENT OBTAINED USING THE SAME FUJIFILM CORPORATION (JP) 2015-05-14 US disclosed
US-20140042411-A1 METHOD FOR PURIFYING ORGANIC MATERIAL, MATERIAL FOR ORGANIC ELECTRONICS, PHOTOELECTRIC CONVERSION DEVICE, OPTICAL SENSOR, IMAGING DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2014-02-13 US disclosed
US-8461572-B2 Organic luminescent device and manufacturing method thereof DENSO CORPORATION (JP) 2013-06-11 US disclosed
US-20110006288-A1 ORGANIC LUMINESCENT DEVICE AND MANUFACTURING METHOD THEREOF DENSO CORPORATION 2011-01-13 US disclosed