SCHEMBL6705565

SCHEMBL6705565

CC(C)(C)c1ccc(N(c2ccc(N(c3ccc(N(c4ccc(C(C)(C)C)cc4)c4ccc(C(C)(C)C)cc4)cc3)c3ccc(N(c4ccc(C(C)(C)C)cc4)c4ccc(C(C)(C)C)cc4)cc3)cc2)c2ccc(C(C)(C)C)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
LMNA P02545 1/20 0.50
TYR P14679 1/20 0.50
KIF11 P52732 2/20 0.42
ALDH1A1 P00352 5/20 0.41
HPGD P15428 2/20 0.39
NPC1 O15118 1/20 0.39
MAPT P10636 1/20 0.39
MAPK1 P28482 1/20 0.39
RAB9A P51151 1/20 0.39
HDAC1 Q13547 1/20 0.39
SLC22A2 O15244 1/20 0.39
SLC22A1 O15245 1/20 0.39
SLC22A3 O75751 1/20 0.39
HSD17B10 Q99714 2/20 0.39
KCNH2 Q12809 1/20 0.39
BCHE P06276 3/20 0.39
ACHE P22303 3/20 0.39
ALOX15 P16050 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14163841 1.00 TSHR (0.52) TSHRLMNATYRKIF11ALDH1A1
SCHEMBL13136660 1.00 TSHR (0.52) TSHRLMNATYRKIF11ALDH1A1
SCHEMBL12951069 0.92 KIF11 (0.54) TSHRLMNATYRKIF11ALDH1A1
SCHEMBL8642413 0.92 KIF11 (0.54) TSHRLMNATYRKIF11ALDH1A1
SCHEMBL16343998 0.92 KIF11 (0.54) TSHRLMNATYRKIF11ALDH1A1
SCHEMBL14163852 0.90 L3MBTL1 (0.50) TSHRLMNATYRKIF11ALDH1A1
SCHEMBL19996361 0.90 TSHR (0.71) TSHRLMNATYRKIF11ALDH1A1
SCHEMBL6935203 0.90 L3MBTL1 (0.50) TSHRLMNATYRKIF11ALDH1A1
SCHEMBL21227694 0.90 SLC2A1 (0.54) TSHRLMNATYRALDH1A1HPGD
SCHEMBL15746013 0.90 L3MBTL1 (0.50) TSHRLMNATYRKIF11ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220406850-A1 PHOTODETECTOR ELEMENT AND IMAGE SENSOR FUJIFILM CORPORATION (JP) 2022-12-22 US disclosed
JP-2004087130-A ORGANIC ELECTROLUMINESCENT ELEMENT AND ITS MANUFACTURING METHOD VICTOR CO OF JAPAN LTD 2004-03-18 JP disclosed