SCHEMBL12952010

SCHEMBL12952010

CCc1ccc(P(=O)(C(=O)c2ccccc2)C(=O)c2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
PLK1 P53350 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
TP53 P04637 1/20 0.43
TAS2R14 Q9NYV8 1/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
RAB9A P51151 4/20 0.40
NPC1 O15118 3/20 0.40
SRC P12931 1/20 0.40
PTGS2 P35354 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
GAA P10253 1/20 0.40
PKM P14618 1/20 0.40
KLF5 Q13887 1/20 0.40
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL345381 0.81 ALDH1A1 (0.52) ALDH1A1MEN1KMT2ATSHRRAB9A
SCHEMBL1032933 0.79 ALDH1A1 (0.53) ALDH1A1PLK1MEN1KMT2ATP53
Ethylene SCHEMBL27614434 0.77 ALDH1A1 (0.48) ALDH1A1MEN1KMT2ATSHRRAB9A
SCHEMBL975055 0.77 ALDH1A1 (0.65) ALDH1A1PLK1TP53HPGDRAB9A
Ammonia Solution, Strong SCHEMBL8465674 0.76 ALDH1A1 (0.63) ALDH1A1PLK1TP53HPGDRAB9A
Benzophenone SCHEMBL28116793 0.75 ALDH1A1 (0.64) ALDH1A1MEN1KMT2ATP53HPGD
SCHEMBL31038283 0.74 TP53 (0.50) ALDH1A1MEN1KMT2ATP53TSHR
Ammonia Solution, Strong SCHEMBL28944620 0.74 RARB (0.55) ALDH1A1PLK1MEN1KMT2A
SCHEMBL2836495 0.74 ALDH1A1 (0.65) ALDH1A1PLK1TP53RAB9AGAA
SCHEMBL18022804 0.74 LMNA (0.60) ALDH1A1MEN1KMT2ATP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7862886-B2 Optical film, antireflection film, processes for producing the same, and polarizing plate and display employing the same FUJIFILM CORPORATION (JP) 2011-01-04 US disclosed