Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL823327 | 0.85 | MAPT (0.48) | SLC2A1ALDH1A1L3MBTL1PIK3CAKDM4E | |
| SCHEMBL12894055 | 0.80 | MAPT (0.44) | SLC2A1LRRK2ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL823396 | 0.80 | L3MBTL1 (0.47) | ALDH1A1L3MBTL1KDM4EMAPTHTT | |
| SCHEMBL1221906 | 0.79 | MEN1 (0.42) | SLC2A1LRRK2ALDH1A1L3MBTL1PIK3CB | |
| SCHEMBL823395 | 0.78 | CYP2C9 (0.51) | ALDH1A1KDM4EHTTHPGDSMN1; SMN2 | |
| SCHEMBL823378 | 0.78 | SLC2A1 (0.52) | SLC2A1ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL823367 | 0.77 | RXFP1 (0.50) | SLC2A1ALDH1A1PIK3CAPIK3CBPIK3CG | |
| SCHEMBL823382 | 0.77 | ERCC1 (0.45) | SLC2A1MAPTHTT | |
| SCHEMBL823331 | 0.76 | THRB (0.51) | ALDH1A1KDM4EMAPTHTTCYP1A2 | |
| SCHEMBL12166740 | 0.74 | CSNK1D (0.43) | SLC2A1ALDH1A1KDM4EMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2269992-A1 | Bicyclic pyrimidinones for the treatment of viral infections | Avexa Limited (AU) | 2011-01-05 | — | — | EP | disclosed |