Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1014813 | 0.91 | DPP4 (0.38) | DPP4DPP8DPP7DPP9TLR9 | |
| SCHEMBL1602971 | 0.87 | DPP4 (0.47) | DPP4DPP8DPP7DPP9TLR9 | |
| SCHEMBL12953419 | 0.86 | RAB9A (0.44) | DPP4DPP8DPP7DPP9TLR9 | |
| SCHEMBL1017044 | 0.85 | NPC1 (0.42) | DPP4DPP8DPP7DPP9NPC1 | |
| SCHEMBL1016633 | 0.85 | DPP4 (0.44) | DPP4DPP8DPP7DPP9TLR9 | |
| SCHEMBL1020593 | 0.85 | DPP4 (0.41) | DPP4DPP8DPP7DPP9TLR9 | |
| SCHEMBL12953415 | 0.84 | RAB9A (0.43) | DPP4DPP8DPP7DPP9TLR9 | |
| SCHEMBL1017927 | 0.84 | DPP4 (0.47) | DPP4DPP8DPP7DPP9TLR9 | |
| SCHEMBL1017930 | 0.84 | PDCD1 (0.42) | NPC1RAB9AHRH3IRAK4ALDH1A1 | |
| SCHEMBL1017188 | 0.83 | NPC1 (0.42) | DPP4DPP8DPP7DPP9TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1998620-B1 | PIPERAZINYL OXOALKYL TETRAHYDROISOQUINOLINES AND RELATED ANALOGUES | NEUROGEN CORP (US) | 2011-01-12 | — | — | EP | disclosed |