SCHEMBL129533

SCHEMBL129533

CCCCCCCCCCC=CS

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 6/20 0.54
TRPV1 Q8NER1 1/20 0.54
TSHR P16473 2/20 0.48
TERT O14746 3/20 0.46
CYP1A2 P05177 2/20 0.46
MAPT P10636 2/20 0.46
CYP2C19 P33261 2/20 0.46
BLM P54132 2/20 0.46
HSD17B10 Q99714 2/20 0.46
FABP4 P15090 2/20 0.46
PTPN1 P18031 2/20 0.46
PPARG P37231 2/20 0.46
KMT2A Q03164 2/20 0.46
PPARD Q03181 2/20 0.46
PPARA Q07869 2/20 0.46
GMNN O75496 1/20 0.46
USP2 O75604 1/20 0.46
LMNA P02545 1/20 0.46
POLB P06746 1/20 0.46
CYP2C9 P11712 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL448357 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTCYP1A2
SCHEMBL129511 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTCYP1A2
SCHEMBL448718 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTCYP1A2
SCHEMBL450997 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTCYP1A2
SCHEMBL10959408 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTCYP1A2
SCHEMBL9366273 1.00
SCHEMBL135854 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTCYP1A2
SCHEMBL9362653 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTCYP1A2
SCHEMBL10959317 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTCYP1A2
SCHEMBL10955670 1.00 FAAH (0.54) FAAHTRPV1TSHRTERTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1414873-B1 ENHANCED POLYMERIZATION PROCESS SABIC INNOVATIVE PLASTICS IP (NL) 2008-12-03 EP claimed
EP-1200496-B1 PROCESS FOR THE MANUFACTURE OF IMPACT RESISTANT MODIFIED POLYMERS BAYER AG (US) 2004-03-10 EP claimed
CN-111748349-A Quantum dot and manufacturing method thereof 拓米(成都)应用技术研究院有限公司 2020-10-09 CN disclosed
EP-3090000-B1 HYDROGENATED NITRILE RUBBER CONTAINING PHOSPHINE OR DIPHOSPHANE OXIDE ARLANXEO DEUTSCHLAND GMBH (DE) 2019-10-02 EP disclosed
EP-3090002-B1 HYDROGENATED NITRILE RUBBER CONTAINING PHOSPHINE OR DIPHOSPHANE OXIDE ARLANXEO DEUTSCHLAND GMBH (DE) 2019-10-02 EP disclosed
EP-2883865-B1 Compound capable of binding S1P receptor and pharmaceutical use thereof ONO PHARMACEUTICAL CO (JP) 2019-09-25 EP disclosed
EP-3283538-B1 POWDER FORM MIXTURES CONTAINING LOW-EMISSION NITRILE RUBBERS ARLANXEO DEUTSCHLAND GMBH (DE) 2019-06-19 EP disclosed
EP-3283538-A1 PULVERULENT MIXTURES CONTAINING LOW-EMISSION NITRILE RUBBERS ARLANXEO Deutschland GmbH (DE) 2018-02-21 EP disclosed
EP-2860197-B1 Nitrile rubbers with low emissions ARLANXEO DEUTSCHLAND GMBH (DE) 2017-04-19 EP disclosed
EP-2162430-B1 MERCAPTAN MIXTURE ARLANXEO DEUTSCHLAND GMBH (DE) 2016-11-30 EP disclosed
EP-3090002-A1 HYDROGENATED NITRILE RUBBER CONTAINING PHOSPHINE OXIDE OR DIPHOSPHINE OXIDE ARLANXEO Deutschland GmbH (DE) 2016-11-09 EP disclosed
US-20040259877-A1 Inhibitors against the production and release of inflammatory cytokines INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) 2004-12-23 US disclosed
EP-1352650-A1 INHIBITORS AGAINST THE PRODUCTION AND RELEASE OF INFLAMMATORY CYTOKINES Institute of Medicinal Molecular Design, Inc. (JP) 2003-10-15 EP disclosed
EP-0694337-B1 Method for reducing microfoam in a spray-applied waterborne thermoset composition ROHM & HAAS (US) 1999-02-10 EP disclosed
EP-0694337-A1 Method for reducing microfoam in a spray-applied waterborne thermoset composition ROHM AND HAAS COMPANY (US) 1996-01-31 EP disclosed
EP-0354460-B1 Process to produce organosulfur compounds PHILLIPS PETROLEUM CO (US) 1994-04-13 EP disclosed
EP-0354460-A1 Process to produce organosulfur compounds PHILLIPS PETROLEUM COMPANY (US) 1990-02-14 EP disclosed
EP-0243016-B1 N, S CONTAINING CORROSION INHIBITORS EXXON CHEMICAL PATENTS INC. (US) 1989-12-06 EP disclosed
EP-0243016-A1 N, S containing corrosion inhibitors EXXON CHEMICAL PATENTS INC. (US) 1987-10-28 EP disclosed
US-4673436-A THIO SUBSTITUTED QUATERNARY AMMONIUM SALTA EXXON CHEMICAL PATENTS INC. (US) 1987-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040259877-A1 Inhibitors against the production and release of inflammatory cytokines NFKBIA, IL1B, IKBKB FAAH 1462/4885TRPV1 1398/4885TSHR 4035/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.