Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 15/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1295535 | 0.96 | GPR119 (0.46) | GPR119KCNH2CHRM4KDM4EALDH1A1 | |
| SCHEMBL1296758 | 0.90 | GPR119 (0.53) | GPR119KCNH2CHRM4KDM4EALDH1A1 | |
| SCHEMBL1296247 | 0.90 | GPR119 (0.45) | GPR119KCNH2CHRM4CHRM2CHRM1 | |
| SCHEMBL2387633 | 0.89 | GPR119 (0.44) | GPR119KCNH2 | |
| SCHEMBL1296173 | 0.89 | GPR119 (0.45) | GPR119CHRM4CHRM2CHRM1CHRM3 | |
| SCHEMBL1296259 | 0.88 | GPR119 (0.43) | GPR119KCNH2CHRM4 | |
| SCHEMBL1295205 | 0.88 | GPR119 (0.43) | GPR119KCNH2CHRM4 | |
| SCHEMBL1295202 | 0.88 | GPR119 (0.43) | GPR119KCNH2CHRM4 | |
| SCHEMBL1295434 | 0.88 | GPR119 (0.45) | GPR119KCNH2CHRM4 | |
| SCHEMBL1295438 | 0.88 | GPR119 (0.45) | GPR119KCNH2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269734-A1 | PIPERIDINYL GPCR AGONISTS | PROSIDION LIMITED (GB) | 2011-11-03 | — | — | US | disclosed |
| US-20110269734-A1 | PIPERIDINYL GPCR AGONISTS | PROSIDION LIMITED (GB) | 2011-11-03 | — | — | US | disclosed |
| US-20110269734-A1 | PIPERIDINYL GPCR AGONISTS | PROSIDION LIMITED (GB) | 2011-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269734-A1 | PIPERIDINYL GPCR AGONISTS | GPR119, GPR27, GLP1R | GPR119 1/4885KCNH2 1416/4885CHRM4 707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.