Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 4/20 | 0.51 |
| ▸ | DRD4 | P21917 | 4/20 | 0.51 |
| ▸ | DRD3 | P35462 | 4/20 | 0.51 |
| ▸ | PPARG | P37231 | 11/20 | 0.49 |
| ▸ | PPARA | Q07869 | 8/20 | 0.49 |
| ▸ | PPARD | Q03181 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | FABP2 | P12104 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1010345 | 0.94 | DRD4 (0.55) | TAAR1DRD2DRD4DRD3PPARG | |
| SCHEMBL12953103 | 0.92 | PPARG (0.50) | TAAR1DRD2DRD4DRD3PPARG | |
| SCHEMBL1010079 | 0.86 | KMT2A (0.54) | TAAR1PPARGPPARAPPARDMEN1 | |
| SCHEMBL12953477 | 0.85 | DRD2 (0.51) | DRD2DRD4DRD3PPARGMEN1 | |
| SCHEMBL12953100 | 0.82 | PPARA (0.68) | TAAR1PPARGPPARAPPARDMEN1 | |
| SCHEMBL12953438 | 0.82 | KMT2A (0.50) | DRD2DRD4DRD3PPARGMEN1 | |
| SCHEMBL12954041 | 0.80 | TAAR1 (0.63) | TAAR1DRD2DRD4DRD3PPARG | |
| SCHEMBL8108539 | 0.79 | PPARA (0.65) | PPARGPPARAPPARDMEN1KMT2A | |
| SCHEMBL12953097 | 0.77 | PPARG (0.71) | TAAR1PPARGPPARAPPARDMEN1 | |
| SCHEMBL12953073 | 0.76 | PPARA (0.63) | TAAR1PPARGPPARAPPARDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1661890-B1 | PPAR-ACTIVATING COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | KOWA CO (JP) | 2011-01-05 | — | — | EP | disclosed |