Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.65 |
| ▸ | PPARG | P37231 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | FABP2 | P12104 | 2/20 | 0.65 |
| ▸ | PPARD | Q03181 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11569958 | 0.81 | ALDH1A1 (0.51) | PPARAPPARGALDH1A1FABP2PPARD | |
| SCHEMBL12954039 | 0.79 | TAAR1 (0.58) | PPARAPPARGALDH1A1FABP2PPARD | |
| Bezafibrate SCHEMBL16299 | 0.79 | PPARA (1.00) | PPARAPPARGALDH1A1FABP2PPARD | |
| Bezafibrate SCHEMBL5077755 | 0.79 | PPARA (1.00) | PPARAPPARGALDH1A1FABP2PPARD | |
| Bezafibrate SCHEMBL28565716 | 0.78 | PPARA (0.98) | PPARAPPARGALDH1A1FABP2PPARD | |
| Bezafibrate SCHEMBL22364278 | 0.78 | PPARA (0.98) | PPARAPPARGALDH1A1FABP2PPARD | |
| Bezafibrate SCHEMBL3088387 | 0.78 | PPARA (0.98) | PPARAPPARGALDH1A1FABP2PPARD | |
| SCHEMBL14975400 | 0.77 | NPC1 (0.61) | PPARAPPARGALDH1A1FABP2PPARD | |
| SCHEMBL11285273 | 0.76 | PPARA (0.53) | PPARAPPARGALDH1A1FABP2PPARD | |
| SCHEMBL1010079 | 0.76 | KMT2A (0.54) | PPARAPPARGALDH1A1FABP2PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121299-A | Modulating inflammation with cytochrome P-450 activators and inhibitors | LOVELACE RESPIRATORY RESEARCH INSTITUTE (US) | 2000-09-19 | — | — | US | disclosed |