Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | FABP3 | P05413 | 3/20 | 0.43 |
| ▸ | FABP4 | P15090 | 3/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.41 |
| ▸ | PSIP1 | O75475 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 3/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12630015 | 0.84 | KDM4E (0.47) | KDM4EFABP3FABP4PLA2G2AFABP5 | |
| SCHEMBL12630026 | 0.84 | KDM4E (0.47) | KDM4EFABP3FABP4PLA2G2AFABP5 | |
| SCHEMBL12630014 | 0.83 | KDM4E (0.46) | KDM4EFABP3FABP4PLA2G2AFABP5 | |
| SCHEMBL12630010 | 0.81 | KDM4E (0.47) | KDM4EFABP3FABP4PLA2G2AFABP5 | |
| SCHEMBL12956133 | 0.78 | KDM4E (0.44) | KDM4EFABP3FABP4PLA2G2AFABP5 | |
| SCHEMBL12630032 | 0.77 | PSIP1 (0.52) | KDM4EFABP3FABP4PLA2G2AFABP5 | |
| SCHEMBL12630033 | 0.77 | PSIP1 (0.60) | KDM4EFABP3FABP4PLA2G2AFABP5 | |
| SCHEMBL12630016 | 0.76 | KDM4E (0.62) | KDM4EFABP3FABP4PLA2G2AFABP5 | |
| SCHEMBL12956134 | 0.74 | FABP4 (0.57) | KDM4EFABP3FABP4PLA2G2AFABP5 | |
| SCHEMBL14390974 | 0.73 | KDM4E (0.78) | KDM4EFABP3FABP4PLA2G2AFABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2019825-B9 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | BOEHRINGER INGELHEIM INT (DE) | 2011-01-26 | — | — | EP | disclosed |
| EP-2019825-B1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | BOEHRINGER INGELHEIM INT (DE) | 2010-09-01 | — | — | EP | disclosed |