Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1043280 | 0.82 | CNR2 (0.42) | RXFP1LMNAALDH1A1TP53MAPT | |
| SCHEMBL11948678 | 0.80 | KDM4E (0.47) | RXFP1LMNAALDH1A1TP53MAPT | |
| SCHEMBL15085009 | 0.80 | NR4A2 (0.58) | LMNAALDH1A1TP53MAPTHPGD | |
| SCHEMBL11948640 | 0.78 | LMNA (0.49) | RXFP1LMNAALDH1A1TP53MAPT | |
| SCHEMBL11948674 | 0.78 | LMNA (0.45) | LMNAALDH1A1TP53MAPTPOLB | |
| SCHEMBL11948639 | 0.78 | LMNA (0.54) | LMNAALDH1A1HPGD | |
| SCHEMBL11948653 | 0.77 | LMNA (0.47) | LMNAALDH1A1HPGD | |
| SCHEMBL11948645 | 0.76 | ALDH1A1 (0.48) | RXFP1LMNAALDH1A1TP53MAPT | |
| SCHEMBL11948650 | 0.76 | POLB (0.43) | RXFP1LMNAALDH1A1TP53MAPT | |
| SCHEMBL11948647 | 0.76 | LMNA (0.46) | LMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2272516-A2 | 4-Oxoquinoline compound and use thereof as HIV integrase inhibitor | Japan Tobacco, Inc. (JP) | 2011-01-12 | — | — | EP | disclosed |