Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13496361 | 0.94 | HDAC1 (0.41) | MAPTPOLBKDM4ELMNAHTT | |
| SCHEMBL12287021 | 0.80 | ADRA1D (0.45) | POLBKDM4EJAK2JAK1TYK2 | |
| SCHEMBL12959278 | 0.78 | JAK2 (0.40) | MAPTPOLBKDM4ELMNAHTT | |
| SCHEMBL12959357 | 0.78 | BCHE (0.39) | MAPTPOLBKDM4ELMNAJAK2 | |
| SCHEMBL12958598 | 0.72 | OPRK1 (0.39) | MAPTRAB9AJAK2JAK1TYK2 | |
| Trifluoroacetic Acid SCHEMBL1053580 | 0.72 | MEN1 (0.55) | MAPTPOLBKDM4ELMNAHTT | |
| SCHEMBL12958643 | 0.72 | MEN1 (0.57) | MAPTPOLBKDM4ELMNAHTT | |
| SCHEMBL12960042 | 0.70 | JAK2 (0.33) | JAK2JAK1TYK2JAK3CYP1A2 | |
| SCHEMBL12959013 | 0.70 | HDAC1 (0.40) | MAPTPOLBKDM4ELMNAHTT | |
| Trifluoroacetic Acid SCHEMBL864102 | 0.66 | MEN1 (0.56) | MAPTPOLBKDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011008247-A1 | FLAVIN DERIVATIVES | BIORELIX, INC. (US) | 2011-01-20 | — | — | WO | disclosed |