Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12959643 | 0.86 | ALDH1A1 (0.38) | SMN1; SMN2LMNAKDM4EMEN1KMT2A | |
| SCHEMBL12959642 | 0.81 | KDM4E (0.37) | SMN1; SMN2LMNAHTTKDM4EMEN1 | |
| SCHEMBL13965827 | 0.78 | KDM4E (0.39) | SMN1; SMN2LMNAHTTKDM4EMEN1 | |
| SCHEMBL12959301 | 0.78 | MEN1 (0.59) | SMN1; SMN2LMNAHTTKDM4EMEN1 | |
| SCHEMBL12958598 | 0.73 | OPRK1 (0.39) | MCHR1MAPTTP53RAB9A | |
| SCHEMBL12960044 | 0.69 | CYP1A2 (0.41) | SMN1; SMN2LMNAHTTKDM4EMEN1 | |
| SCHEMBL12960017 | 0.67 | MEN1 (0.60) | SMN1; SMN2LMNAHTTKDM4EMEN1 | |
| SCHEMBL12959278 | 0.67 | JAK2 (0.40) | SMN1; SMN2LMNAHTTKDM4EMEN1 | |
| SCHEMBL12958989 | 0.66 | PRKCI (0.43) | HTTKDM4EUSP2MAPTGAA | |
| SCHEMBL13496361 | 0.66 | HDAC1 (0.41) | SMN1; SMN2LMNAHTTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011008247-A1 | FLAVIN DERIVATIVES | BIORELIX, INC. (US) | 2011-01-20 | — | — | WO | disclosed |