SCHEMBL129602

SCHEMBL129602

CCO[Si](CCCCN1CCN([Si](C)(C)C)CC1)(OCC)OCC

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 2/20 0.33
GNAO1 P09471 2/20 0.33
GNAI1 P63096 2/20 0.33
PAOX Q6QHF9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL132262 0.95 GNAI3 (0.30) GNAI3GNAO1GNAI1
SCHEMBL4060043 0.88 GNAI3 (0.33) GNAI3GNAO1GNAI1PAOX
SCHEMBL4063620 0.88
Piperazine SCHEMBL28868943 0.88 CXCR4 (0.33) GNAI3GNAO1GNAI1
SCHEMBL4066942 0.87 PAOX (0.34) GNAI3GNAO1GNAI1PAOX
SCHEMBL19970655 0.86
SCHEMBL4062655 0.85 GNAI3 (0.32) GNAI3GNAO1GNAI1
SCHEMBL130373 0.85
SCHEMBL4060527 0.84 HRH3 (0.30)
SCHEMBL8758990 0.84 GNAI3 (0.35) GNAI3GNAO1GNAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7569691-B2 Protected piperazino group-bearing organoxysilane compound and making method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-08-04 US claimed
CN-109384982-B Modified conjugated diene polymer composition and tire 旭化成株式会社 2020-11-17 CN disclosed
CN-109384981-A Modified conjugated diene rubber composition and tire 旭化成株式会社 2019-02-26 CN disclosed
EP-2615134-B1 RUBBER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF, AND TIRE JSR CORP (JP) 2018-07-18 EP disclosed
EP-2676994-B1 RUBBER COMPOSITION, METHOD FOR PRODUCING SAME, AND TIRE JSR CORP (JP) 2018-01-03 EP disclosed
EP-2674456-B1 RUBBER COMPOSITION, METHOD FOR PRODUCING SAME, AND TIRE JSR CORP (JP) 2017-11-01 EP disclosed
EP-2492286-B1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE RUBBER, MODIFIED CONJUGATED DIENE RUBBER, AND RUBBER COMPOSITION JSR CORP (JP) 2017-04-05 EP disclosed
US-9550840-B2 Process for production of modified conjugated diene rubber, modified conjugated diene rubber, and rubber composition JSR CORPORATION (JP) 2017-01-24 US disclosed
EP-2407507-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE JSR CORP (JP) 2016-09-28 EP disclosed
EP-2676995-B1 RUBBER COMPOSITION, PRODUCTION METHOD THEREFOR AND TIRE JSR CORP (JP) 2016-06-15 EP disclosed
EP-2338919-A1 MODIFIED CONJUGATED DIENE POLYMER, METHOD FOR PRODUCING THE SAME, MODIFIED CONJUGATED DIENE POLYMER COMPOSITION, AND TIRE Asahi Kasei Chemicals Corporation (JP) 2011-06-29 EP disclosed
US-7915349-B2 Conjugated diene polymer and process for production thereof ASAHI KASEI CHEMICALS CORPORATION (JP) 2011-03-29 US disclosed
CN-101765636-A Rubber composition for footwear ASAHI CHEMICAL CORP (JP) 2010-06-30 CN disclosed
US-7569691-B2 Protected piperazino group-bearing organoxysilane compound and making method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-08-04 US disclosed
US-20090163668-A1 Conjugated Diene Polymer and Process for Production Thereof ASAHI KASEI CHEMICALS CORPORATION (JP) 2009-06-25 US disclosed
CN-101268107-A Conjugated diene polymer and process for production thereof ASAHI CHEMICAL CORP (JP) 2008-09-17 CN disclosed
EP-1714968-B1 Protected piperazino group-bearing organoxysilane compound and making method SHINETSU CHEMICAL CO (JP) 2008-07-16 EP disclosed
EP-1942120-A1 CONJUGATED DIENE POLYMER AND PROCESS FOR PRODUCTION THEREOF Asahi Kasei Chemicals Corporation (JP) 2008-07-09 EP disclosed
US-20060241294-A1 Protected piperazino group-bearing organoxysilane compound and making method SHIN-ETSU CHEMICAL CO., LTD. 2006-10-26 US disclosed
EP-1714968-A1 Protected piperazino group-bearing organoxysilane compound and making method Shin-Etsu Chemical Co., Ltd. (JP) 2006-10-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060241294-A1 Protected piperazino group-bearing organoxysilane compound and making method PIEZO1, VCL, VIM GNAI3 2419/4885GNAO1 646/4885GNAI1 2561/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.