Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 5/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12930005 | 0.86 | MEN1 (0.46) | PTGS2KMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL12930022 | 0.77 | CYP2C9 (0.43) | PTGS2KMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL409808 | 0.77 | CA1 (0.41) | PTGS2KMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL31159872 | 0.74 | CA1 (0.38) | PTGS2KMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL25883310 | 0.73 | PTGS2 (0.68) | PTGS2KMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL11978719 | 0.72 | PTGER1 (0.55) | PTGS2KMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL15748689 | 0.71 | CA1 (0.41) | PTGS2KMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL10227709 | 0.71 | CCNA2 (0.40) | PTGS2KMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL411222 | 0.71 | CACNA1G (0.44) | PTGS2KMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL31042823 | 0.70 | CA1 (0.40) | PTGS2KMT2AMEN1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110015401-A1 | Metal-Catalyzed Carbon-Fluorine Bond Formation | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015401-A1 | Metal-Catalyzed Carbon-Fluorine Bond Formation | FLI1, VGF, GMFG | PTGS2 3853/4885KMT2A 196/4885MEN1 1569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.