Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 20/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 17/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12930589 | 0.94 | HRH1 (0.61) | HRH1CYP2D6KCNH2CHRM1ADRA2A | |
| SCHEMBL12930601 | 0.92 | HRH1 (0.63) | HRH1CYP2D6KCNH2CHRM1ADRA2A | |
| SCHEMBL22267802 | 0.90 | HRH1 (0.60) | HRH1CYP2D6KCNH2CHRM1ADRA2A | |
| SCHEMBL12930626 | 0.90 | HRH1 (0.61) | HRH1CYP2D6KCNH2CHRM1ADRA2A | |
| SCHEMBL12930580 | 0.90 | HRH1 (0.62) | HRH1CYP2D6KCNH2CHRM1ADRA2A | |
| SCHEMBL12930631 | 0.90 | HRH1 (0.62) | HRH1CYP2D6KCNH2CHRM1ADRA2A | |
| SCHEMBL12930692 | 0.89 | HRH1 (0.63) | HRH1CYP2D6KCNH2CHRM1ADRA2A | |
| SCHEMBL12930584 | 0.89 | HRH1 (0.65) | HRH1CYP2D6KCNH2CHRM1ADRA2A | |
| SCHEMBL12930579 | 0.89 | HRH1 (0.65) | HRH1CYP2D6KCNH2CHRM1ADRA2A | |
| SCHEMBL12930665 | 0.89 | HRH1 (0.59) | HRH1CYP2D6KCNH2CHRM1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110003828-A1 | PRODRUGS OF NH-ACIDIC COMPOUNDS | ALKERMES, INC. | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003828-A1 | PRODRUGS OF NH-ACIDIC COMPOUNDS | SI, NAAA, NIT2 | HRH1 153/4885CYP2D6 263/4885KCNH2 2863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.