Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 8/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1296154 | 1.00 | GPR119 (0.43) | GPR119KCNH2ACACB | |
| SCHEMBL1296480 | 0.93 | GPR119 (0.44) | GPR119KCNH2ACACB | |
| SCHEMBL1296483 | 0.93 | GPR119 (0.44) | GPR119KCNH2ACACB | |
| SCHEMBL1296208 | 0.92 | GPR119 (0.43) | GPR119KCNH2ACACB | |
| SCHEMBL1296210 | 0.92 | GPR119 (0.43) | GPR119KCNH2ACACB | |
| SCHEMBL1296481 | 0.88 | GPR119 (0.47) | GPR119KCNH2ACACB | |
| SCHEMBL1296250 | 0.87 | GPR119 (0.45) | GPR119KCNH2ACACB | |
| SCHEMBL1296246 | 0.87 | GPR119 (0.45) | GPR119KCNH2ACACB | |
| SCHEMBL1295769 | 0.82 | GPR119 (0.46) | GPR119KCNH2ACACB | |
| SCHEMBL1295833 | 0.79 | GPR119 (0.47) | GPR119KCNH2ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269734-A1 | PIPERIDINYL GPCR AGONISTS | PROSIDION LIMITED (GB) | 2011-11-03 | — | — | US | disclosed |
| US-20110269734-A1 | PIPERIDINYL GPCR AGONISTS | PROSIDION LIMITED (GB) | 2011-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269734-A1 | PIPERIDINYL GPCR AGONISTS | GPR119, GPR27, GLP1R | GPR119 1/4885KCNH2 1416/4885ACACB 3305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.