Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | SGMS2 | Q8NHU3 | 5/20 | 0.39 |
| ▸ | SGMS1 | Q86VZ5 | 4/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1295379 | 0.84 | GPR119 (0.54) | GPR119FAAHSCN9A | |
| SCHEMBL1296187 | 0.83 | GPR119 (0.48) | GPR119FAAHSCN9A | |
| SCHEMBL1296046 | 0.81 | GPR119 (0.52) | GPR119FAAHSCN9A | |
| SCHEMBL1295859 | 0.77 | GPR119 (0.64) | GPR119FAAH | |
| SCHEMBL1837944 | 0.76 | GPR119 (0.61) | GPR119SGMS2SGMS1 | |
| SCHEMBL1575189 | 0.75 | GPR119 (0.71) | GPR119SCN9A | |
| SCHEMBL20061052 | 0.74 | GPR119 (0.62) | GPR119FAAHSGMS2SGMS1 | |
| SCHEMBL1295284 | 0.73 | GPR119 (0.49) | GPR119 | |
| SCHEMBL1295288 | 0.73 | GPR119 (0.49) | GPR119 | |
| SCHEMBL20061051 | 0.72 | GPR119 (0.59) | GPR119FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269734-A1 | PIPERIDINYL GPCR AGONISTS | PROSIDION LIMITED (GB) | 2011-11-03 | — | — | US | disclosed |
| EP-2321297-A1 | PIPERIDINYL GPCR AGONISTS | Prosidion Limited (GB) | 2011-05-18 | — | — | EP | disclosed |
| WO-2010004343-A1 | PIPERIDINYL GPCR AGONISTS | PROSIDION LIMITED (GB) | 2010-01-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269734-A1 | PIPERIDINYL GPCR AGONISTS | GPR119, GPR27, GLP1R | GPR119 1/4885FAAH 269/4885SGMS2 1305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.