SCHEMBL12961963

SCHEMBL12961963

CC1C[C@H](Oc2ccc(C(F)(F)F)cc2C2(C)OCCO2)CCN1c1ccc(C(F)(F)F)cn1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CXCR3 P49682 7/20 0.38
CNR2 P34972 4/20 0.37
CNR1 P21554 3/20 0.37
SGPL1 O95470 1/20 0.36
TMEM97 Q5BJF2 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
KDM4E B2RXH2 1/20 0.35
ABL1 P00519 1/20 0.35
LMNA P02545 1/20 0.35
HRH3 Q9Y5N1 2/20 0.35
IKBKE Q14164 1/20 0.34
TBK1 Q9UHD2 1/20 0.34
SCD O00767 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12961964 0.90 CXCR3 (0.40) CXCR3CNR2CNR1KDM4EABL1
SCHEMBL13799822 0.83 CXCR3 (0.37) CXCR3TMEM97SIGMAR1KDM4EABL1
SCHEMBL10107298 0.83 CXCR3 (0.37) CXCR3TMEM97SIGMAR1KDM4EABL1
SCHEMBL425105 0.83 CXCR3 (0.37) CXCR3TMEM97SIGMAR1KDM4EABL1
SCHEMBL10107091 0.82 SCD (0.40) CXCR3CNR2CNR1SGPL1KDM4E
SCHEMBL13951318 0.82 CNR2 (0.38) CXCR3CNR2CNR1SGPL1TMEM97
SCHEMBL12961937 0.81 KDM4E (0.40) CXCR3CNR2CNR1SGPL1KDM4E
SCHEMBL385660 0.81 SGPL1 (0.39) CXCR3CNR2CNR1SGPL1KDM4E
SCHEMBL12961901 0.80 IKBKE (0.45) CXCR3CNR2CNR1SGPL1KDM4E
SCHEMBL12962019 0.79 LIPG (0.50) CXCR3CNR2CNR1SGPL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7868178-B2 Cyclic amine compound and pest control agent NIPPON SODA CO., LTD. (JP) 2011-01-11 US disclosed