⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Boric Acid SCHEMBL28709350 | 0.88 | ALDH1A1 (0.38) | — | |
| Lithium Ion SCHEMBL28709347 | 0.84 | ALDH1A1 (0.35) | — | |
| SCHEMBL7170877 | 0.77 | — | — | |
| SCHEMBL3351759 | 0.77 | — | — | |
| SCHEMBL249117 | 0.77 | — | — | |
| SCHEMBL1566869 | 0.77 | — | — | |
| SCHEMBL134556 | 0.77 | — | — | |
| SCHEMBL5162473 | 0.77 | — | — | |
| SCHEMBL19042194 | 0.76 | — | — | |
| SCHEMBL4849399 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4129293-A1 | NERVE CELL DEGENERATION INHIBITOR | Kyoto University (JP) | 2023-02-08 | — | — | EP | disclosed |
| EP-2320886-B1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITION FOR THE TREATMENT OF COLLAPSING GLOMERULOPATHY AND OTHER GLOMERULAR DISEASE | GENZYME CORP (US) | 2017-06-28 | — | — | EP | disclosed |
| WO-2015003958-A1 | AMILORIDE-TYPE COMPOUNDS AS INHIBITORS IN EPITHELIAL SODIUM CHANNELS FOR THE TREATMENT OF DISEASES OF THE LUNGS AND AIRWAYS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-01-15 | — | — | WO | disclosed |
| WO-2011011680-A1 | ISOFORM SELECTIVE PHOSPHOLIPASE D INHIBITORS | VANDERBILT UNIVERSITY (US) | 2011-01-27 | — | — | WO | disclosed |
| WO-2010014554-A1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITION FOR THE TREATMENT OF COLLAPSING GLOMERULOPATHY AND OTHER GLOMERULAR DISEASE | GENZYME CORPORATION (US) | 2010-02-04 | — | — | WO | disclosed |