SCHEMBL129654

SCHEMBL129654

CC(F)c1ccc2cc(C(=O)C3C=NN(C)C3=O)c(C(F)(F)F)nc2n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL124741 0.77 GFER (0.38)
SCHEMBL125072 0.75
SCHEMBL126878 0.73 HPD (0.30)
SCHEMBL122918 0.71 KDM4E (0.48)
SCHEMBL3430681 0.67 GFER (0.38)
SCHEMBL126778 0.65 GFER (0.36)
SCHEMBL126666 0.62 KDM4E (0.48)
SCHEMBL123340 0.62 HPD (0.39)
SCHEMBL3431113 0.62 GFER (0.34)
SCHEMBL126060 0.60 HPD (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8461083-B2 Herbicidal compounds SYNGENTA LIMITED (GB) 2013-06-11 US disclosed
EP-2265120-B1 HERBICIDAL COUMPOUNDS SYNGENTA LTD (GB) 2012-03-07 EP disclosed
US-20110021352-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION, INC. (US) 2011-01-27 US disclosed
EP-2265120-A1 HERBICIDAL COUMPOUNDS Syngenta Limited (GB) 2010-12-29 EP disclosed
WO-2009115788-A1 HERBICIDAL COUMPOUNDS SYNGENTA LIMITED (GB) 2009-09-24 WO disclosed