Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12966651 | 0.87 | RAB9A (0.53) | MAPTRAB9ANPC1DRD2DRD1 | |
| SCHEMBL38663 | 0.82 | PPARA (0.51) | LMNAMAPTRAB9ANPC1L3MBTL1 | |
| SCHEMBL43048 | 0.82 | PPARA (0.51) | LMNAMAPTRAB9ANPC1L3MBTL1 | |
| SCHEMBL12966544 | 0.79 | KMT2A (0.46) | MAPTRAB9ANPC1KMT2AABCB1 | |
| SCHEMBL17988719 | 0.77 | MAPT (0.45) | LMNAMAPTRAB9ANPC1KMT2A | |
| SCHEMBL12490357 | 0.76 | STS (0.55) | LMNAMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL12966622 | 0.76 | NPC1 (0.44) | LMNAMAPTRAB9ANPC1KMT2A | |
| SCHEMBL12966546 | 0.76 | PPARA (0.57) | LMNAMAPTRAB9ANPC1L3MBTL1 | |
| SCHEMBL12966653 | 0.75 | MAPT (0.55) | LMNAMAPTRAB9ANPC1KMT2A | |
| SCHEMBL14699621 | 0.75 | RAB9A (0.55) | LMNAMAPTRAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012130850-A1 | TISSUE TARGETING BY MEANS OF ONCOCIDAL BRIDGED DIPHENYL DERIVATIVES FOR THE SELECTIVE TREATMENT OF SEXUAL ORGAN TUMORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-10-04 | — | — | WO | disclosed |