Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.38 |
| ▸ | GRM6 | O15303 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RORA | P35398 | 1/20 | 0.35 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12966544 | 0.86 | KMT2A (0.46) | MAPTNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL12966650 | 0.84 | MAPT (0.60) | MAPTNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL12966651 | 0.81 | RAB9A (0.53) | MAPTNPC1RAB9AL3MBTL1ABCB1 | |
| SCHEMBL12966898 | 0.78 | MAPT (0.53) | MAPTNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL12966897 | 0.77 | MAPT (0.53) | MAPTNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL17988719 | 0.75 | MAPT (0.45) | MAPTNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL12966550 | 0.75 | LMNA (0.46) | MAPTNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL12490357 | 0.74 | STS (0.55) | MAPTNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL8481702 | 0.74 | LMNA (0.52) | MAPTNPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL12966900 | 0.74 | MAPT (0.59) | MAPTNPC1RAB9AALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012130850-A1 | TISSUE TARGETING BY MEANS OF ONCOCIDAL BRIDGED DIPHENYL DERIVATIVES FOR THE SELECTIVE TREATMENT OF SEXUAL ORGAN TUMORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-10-04 | — | — | WO | disclosed |