Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 2/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12967414 | 0.89 | APP (0.37) | KDM4EL3MBTL1ALDH1A1BRD4TSHR | |
| SCHEMBL12966991 | 0.89 | HTT (0.38) | KDM4EALDH1A1HDAC6NPC1RAB9A | |
| SCHEMBL12964816 | 0.78 | — | — | |
| SCHEMBL12967265 | 0.76 | HDAC6 (0.39) | KDM4EL3MBTL1NAAACASP1ALDH1A1 | |
| SCHEMBL1499693 | 0.68 | HDAC3 (0.46) | KDM4EALDH1A1HDAC6SMN1; SMN2HDAC3 | |
| SCHEMBL1499689 | 0.68 | HDAC3 (0.46) | KDM4EALDH1A1HDAC6SMN1; SMN2HDAC3 | |
| SCHEMBL1499432 | 0.65 | HDAC6 (0.41) | KDM4EALDH1A1HDAC6RAB9ASMN1; SMN2 | |
| SCHEMBL1499435 | 0.65 | HDAC6 (0.41) | KDM4EALDH1A1HDAC6RAB9ASMN1; SMN2 | |
| SCHEMBL12966950 | 0.65 | SNCA (0.48) | BRD4NAMPTHDAC6NPC1RAB9A | |
| SCHEMBL12967415 | 0.65 | IGF1R (0.41) | KDM4EALDH1A1HDAC6SMN1; SMN2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012131656-A2 | COMPOUNDS FOR USE AS THERAPEUTIC AGENTS AFFECTING P53 EXPRESSION AND/OR ACTIVITY | SOCIÉTÉ SPLICOS (FR) | 2012-10-04 | — | — | WO | disclosed |