Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 4/20 | 0.34 |
| ▸ | ACHE | P22303 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13668495 | 0.93 | HTT (0.43) | HTTSMN1; SMN2TDP1L3MBTL1NPC1 | |
| SCHEMBL11993903 | 0.84 | PGR (0.32) | HTTSMN1; SMN2NR3C1 | |
| SCHEMBL19359725 | 0.83 | HTT (0.47) | HTTSMN1; SMN2TDP1L3MBTL1NPC1 | |
| SCHEMBL13082578 | 0.83 | HTT (0.43) | HTTSMN1; SMN2TDP1L3MBTL1NPC1 | |
| SCHEMBL822949 | 0.82 | HTT (0.63) | HTTSMN1; SMN2TDP1L3MBTL1MAPT | |
| SCHEMBL13329348 | 0.80 | NPC1 (0.41) | HTTSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL13670326 | 0.79 | HTT (0.53) | HTTSMN1; SMN2TDP1L3MBTL1MAPT | |
| SCHEMBL12113389 | 0.78 | HTT (0.41) | HTTSMN1; SMN2TDP1L3MBTL1FFAR1 | |
| SCHEMBL13321958 | 0.78 | HTT (0.57) | HTTSMN1; SMN2TDP1L3MBTL1MAPT | |
| SCHEMBL12341727 | 0.78 | HTT (0.57) | HTTSMN1; SMN2TDP1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120251919-A1 | POLYARYLENE-BASED COPOLYMER AND USES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-04 | — | — | US | disclosed |