SCHEMBL12971327

SCHEMBL12971327

N=C(N)NCCCC(NC(=O)CCCCCN)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ SLC6A5 Q9Y345 1/20 0.55
▸ NOD1 Q9Y239 6/20 0.51
▸ FOLH1 Q04609 2/20 0.48
▸ NMT2 O60551 2/20 0.46
▸ NMT1 P30419 2/20 0.46
▸ NPY4R P50391 4/20 0.45
▸ NPY1R P25929 2/20 0.45
▸ NPY2R P49146 2/20 0.45
▸ NPY5R Q15761 2/20 0.45
▸ FNTA P49354 1/20 0.45
▸ FNTB P49356 1/20 0.45
▸ GNPAT O15228 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17304351 1.00 SLC6A5 (0.55) SLC6A5NOD1FOLH1NMT2NMT1
SCHEMBL17304346 1.00 SLC6A5 (0.55) SLC6A5NOD1FOLH1NMT2NMT1
SCHEMBL7275349 1.00 SLC6A5 (0.55) SLC6A5NOD1FOLH1NMT2NMT1
SCHEMBL12971329 1.00 SLC6A5 (0.55) SLC6A5NOD1FOLH1NMT2NMT1
SCHEMBL12971402 0.99 SLC6A5 (0.53) SLC6A5NOD1FOLH1NMT2NMT1
SCHEMBL12971400 0.99 SLC6A5 (0.53) SLC6A5NOD1FOLH1NMT2NMT1
SCHEMBL17304348 0.90 NOD1 (0.52) SLC6A5NOD1FOLH1NPY4RNPY1R
SCHEMBL17304352 0.90 NOD1 (0.52) SLC6A5NOD1FOLH1NPY4RNPY1R
SCHEMBL17304354 0.90 NOD1 (0.52) SLC6A5NOD1FOLH1NPY4RNPY1R
SCHEMBL17304345 0.90 NOD1 (0.52) SLC6A5NOD1FOLH1NPY4RNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111375066-B Compositions and methods for treating cancer 百欧肯治疗有限公司 2023-04-25 — — CN disclosed
CN-115996741-A CXCR4 inhibitors for the treatment of acute respiratory distress syndrome and viral infections 百欧林纳克斯有限公司 2023-04-21 — — CN disclosed
US-11013704-B2 Compounds supports hematopoietic stem cells and red blood cells THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2021-05-25 — — US disclosed
EP-3011961-B1 4F-BENZOYL-TN14003 FOR THE MOBILISATION OF HEMATOPOIETIC PROGENITOR CELLS IN VIEW OF TRANSPLANTATION BIOKINE THERAPEUTICS LTD (IL) 2020-11-11 — — EP disclosed
EP-3419645-B1 METHOD OF SELECTING A TREATMENT REGIMEN IN ACUTE MYELOID LEUKEMIA (AML) BIOLINERX LTD (IL) 2020-09-02 — — EP disclosed
EP-3062809-B1 A CXCR4 PEPTIDE INHIBITOR FOR USE IN TREATING ACUTE MYELOID LEUKEMIA WITH A FLT3 MUTATION BIOKINE THERAPEUTICS LTD (IL) 2020-07-08 — — EP disclosed
CN-111375066-A Compositions and methods for treating cancer 百欧肯治疗有限公司 2020-07-07 — — CN disclosed
US-20170304240-A1 NOVEL COMPOUNDS SUPPORTS HEMATOPOIETIC STEM CELLS AND RED BLOOD CELLS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2017-10-26 — — US disclosed
EP-2978439-B1 A COMBINATION OF A CXCR4 ANTAGONIST AND CYTARABINE FOR USE IN TREATING MYELOID LEUKEMIA BIOKINE THERAPEUTICS LTD (IL) 2017-08-16 — — EP disclosed
WO-2015183545-A1 NOVEL COMPOUNDS SUPPORTS HEMATOPOIETIC STEM CELLS AND RED BLOOD CELLS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2015-12-03 — — WO disclosed
EP-2442822-B1 PEPTIDE THERAPY FOR INCREASING PLATELET LEVELS BIOKINE THERAPEUTICS LTD (IL) 2014-03-05 — — EP disclosed
EP-1898943-B1 CXCR4 ANTAGONISTS FOR WOUND HEALING AND RE-EPITHELIALIZATION HADASIT MED RES SERVICE (IL) 2012-10-10 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170304240-A1 NOVEL COMPOUNDS SUPPORTS HEMATOPOIETIC STEM CELLS AND RED BLOOD CELLS EPOR, THPO, MCL1 SLC6A5 4824/4885NOD1 4864/4885FOLH1 1193/4885
US-11013704-B2 Compounds supports hematopoietic stem cells and red blood cells EPOR, THPO, MCL1 SLC6A5 4711/4885NOD1 4866/4885FOLH1 1061/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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