Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 6/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12972567 | 0.83 | MAPT (0.46) | SIRT6ARCYP3A4LMNASMN1; SMN2 | |
| SCHEMBL12972572 | 0.80 | ALDH1A1 (0.47) | SIRT6ARCYP3A4LMNASMN1; SMN2 | |
| SCHEMBL7569166 | 0.78 | AR (0.45) | SIRT6ARCYP3A4LMNASMN1; SMN2 | |
| SCHEMBL12972551 | 0.78 | AR (0.45) | SIRT6ARCYP3A4LMNASMN1; SMN2 | |
| SCHEMBL16997062 | 0.78 | MMP14 (0.41) | MMP14SMN1; SMN2MAPK1ALDH1A1GLA | |
| SCHEMBL16997057 | 0.77 | MMP14 (0.39) | MMP14ARLMNASMN1; SMN2MAPK1 | |
| SCHEMBL12972722 | 0.76 | MMP14 (0.38) | MMP14ARCYP3A4LMNASMN1; SMN2 | |
| SCHEMBL17787279 | 0.76 | MMP14 (0.63) | MMP14CYP3A4LMNASMN1; SMN2TSHR | |
| SCHEMBL14063276 | 0.76 | MMP14 (0.63) | MMP14CYP3A4LMNASMN1; SMN2TSHR | |
| SCHEMBL5452124 | 0.74 | MAPT (0.60) | SIRT6ARCYP3A4LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7854863-B2 | Functional materials for use in optical systems | BATTELLE MEMORIAL INSTITUTE (US) | 2010-12-21 | — | — | US | disclosed |