SCHEMBL12973871

SCHEMBL12973871

CNC1C(O)O[C@H](COP(=O)(O)O)C(O)[C@@H]1O

nearest known ligand 0.74

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ AMDHD2 Q9Y303 1/20 0.74
▸ FBP1 P09467 1/20 0.64
▸ IGF2R P11717 4/20 0.47
▸ P2RY2 P41231 2/20 0.39
▸ P2RY6 Q15077 1/20 0.39
▸ UMPS P11172 2/20 0.39
▸ ATIC P31939 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25084084 1.00 AMDHD2 (0.74) AMDHD2FBP1IGF2RP2RY2P2RY6
SCHEMBL29394667 0.84 AMDHD2 (0.68) AMDHD2FBP1IGF2RP2RY2
SCHEMBL4363206 0.84 AMDHD2 (0.68) AMDHD2FBP1IGF2RP2RY2
SCHEMBL29425232 0.84 AMDHD2 (0.68) AMDHD2FBP1IGF2RP2RY2
SCHEMBL25361382 0.84 AMDHD2 (0.68) AMDHD2FBP1IGF2RP2RY2
SCHEMBL4363197 0.84 AMDHD2 (0.68) AMDHD2FBP1IGF2RP2RY2
SCHEMBL14669223 0.84 AMDHD2 (0.68) AMDHD2FBP1IGF2RP2RY2
SCHEMBL20558753 0.84 AMDHD2 (0.68) AMDHD2FBP1IGF2RP2RY2
SCHEMBL20912983 0.84 AMDHD2 (0.68) AMDHD2FBP1IGF2RP2RY2
SCHEMBL20291477 0.84 AMDHD2 (0.68) AMDHD2FBP1IGF2RP2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100324123-A1 GLMS RIBOSWITCHES, STRUCTURE-BASED COMPOUND DESIGN WITH GLMS RIBOSWITCHES, AND METHODS AND COMPOSITIONS FOR USE OF AND WITH GLMS RIBOSWITCHES YALE UNIVERSITY (US) 2010-12-23 — — US disclosed
US-20100324123-A1 GLMS RIBOSWITCHES, STRUCTURE-BASED COMPOUND DESIGN WITH GLMS RIBOSWITCHES, AND METHODS AND COMPOSITIONS FOR USE OF AND WITH GLMS RIBOSWITCHES YALE UNIVERSITY (US) 2010-12-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100324123-A1 GLMS RIBOSWITCHES, STRUCTURE-BASED COMPOUND DESIGN WITH GLMS RIBOSWITCHES, AND METHODS AND COMPOSITIONS FOR USE OF AND WITH GLMS RIBOSWITCHES GLMN, RNGTT, GMPS AMDHD2 140/4885FBP1 136/4885IGF2R 935/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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