SCHEMBL12974316

SCHEMBL12974316

CCN(c1ccccc1)c1nc(Cl)nc(Nc2cc(S(=O)(=O)O)cc3cc(S(=O)(=O)O)c(/N=N/c4ccc5ccccc5c4S(=O)(=O)O)c(O)c23)n1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FUT8 Q9BYC5 1/20 0.57
▸ CYP1A2 P05177 5/20 0.45
▸ MAPK1 P28482 2/20 0.45
▸ CYP2C9 P11712 2/20 0.45
▸ DNASE1L3 Q13609 1/20 0.45
▸ ENPP2 Q13822 5/20 0.39
▸ PHLPP2 Q6ZVD8 1/20 0.39
▸ PRMT1 Q99873 1/20 0.38
▸ MEN1 O00255 3/20 0.37
▸ KMT2A Q03164 3/20 0.37
▸ HTT P42858 1/20 0.37
▸ THRB P10828 2/20 0.37
▸ ALDH1A1 P00352 3/20 0.37
▸ HIF1A Q16665 2/20 0.36
▸ MPL P40238 1/20 0.34
▸ CTRC Q99895 1/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34
▸ TSHR P16473 1/20 0.33
▸ PTPRA P18433 1/20 0.33
▸ PTPRB P23467 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12646578 1.00 FUT8 (0.57) FUT8CYP1A2MAPK1CYP2C9DNASE1L3
SCHEMBL14022709 0.93 FUT8 (0.58) FUT8CYP1A2MAPK1CYP2C9DNASE1L3
SCHEMBL12172963 0.93 FUT8 (0.58) FUT8CYP1A2MAPK1CYP2C9DNASE1L3
SCHEMBL19754269 0.93 FUT8 (0.47) FUT8CYP1A2MAPK1CYP2C9DNASE1L3
SCHEMBL12589961 0.92 FUT8 (0.45) FUT8CYP1A2MAPK1CYP2C9DNASE1L3
SCHEMBL12173273 0.92 FUT8 (0.45) FUT8CYP1A2MAPK1CYP2C9DNASE1L3
SCHEMBL12189773 0.91 FUT8 (0.46) FUT8CYP1A2MAPK1CYP2C9DNASE1L3
SCHEMBL881777 0.90 FUT8 (0.52) FUT8CYP1A2MAPK1CYP2C9DNASE1L3
SCHEMBL20008109 0.90 FUT8 (0.52) FUT8CYP1A2MAPK1CYP2C9DNASE1L3
SCHEMBL8628445 0.90 FUT8 (0.71) FUT8CYP1A2MAPK1CYP2C9DNASE1L3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1948738-B1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS BASF SE (DE) 2018-02-28 — — EP disclosed
US-8962140-B2 Functionalized core-shell nanoparticles BASF SE (DE) 2015-02-24 — — US disclosed
US-8962140-B2 Functionalized core-shell nanoparticles BASF SE (DE) 2015-02-24 — — US disclosed
US-8456733-B2 Coloured particles for electrophoretic displays BASF SE (DE) 2013-06-04 — — US disclosed
US-8456733-B2 Coloured particles for electrophoretic displays BASF SE (DE) 2013-06-04 — — US disclosed
US-20130096241-A1 FUNCTIONALIZED NANOPARTICLES BASF SE (DE) 2013-04-18 — — US disclosed
US-20130096241-A1 FUNCTIONALIZED NANOPARTICLES BASF SE (DE) 2013-04-18 — — US disclosed
WO-2010149505-A2 CHARGED PARTICLES BASF SE (DE) 2010-12-29 — — WO disclosed
US-20100162494-A1 FUNCTIONALIZED NANOPARTICLES CIBA CORPORATION (US) 2010-07-01 — — US disclosed
US-20100162494-A1 FUNCTIONALIZED NANOPARTICLES CIBA CORPORATION (US) 2010-07-01 — — US disclosed
US-20090296195-A1 Coloured Particles for Electrophoretic Displays BASF SE (DE) 2009-12-03 — — US disclosed
US-20090296195-A1 Coloured Particles for Electrophoretic Displays BASF SE (DE) 2009-12-03 — — US disclosed
US-7543926-B2 Process for printing textile fibre materials in accordance with the ink-jet printing process HUNTSMAN INTERNATIONAL LLC (US) 2009-06-09 — — US disclosed
US-20070226919-A1 Method for Dyeing or Printing Textile Materials HUNTSMAN INTERNATIONAL LLC (US) 2007-10-04 — — US disclosed
WO-2007048721-A1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS CIBA HOLDING INC. (CH) 2007-05-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090296195-A1 Coloured Particles for Electrophoretic Displays RAB5IF, IK, AOX1 FUT8 382/4885CYP1A2 623/4885MAPK1 1291/4885
US-20100162494-A1 FUNCTIONALIZED NANOPARTICLES TYR, ZKSCAN2, TST FUT8 1659/4885CYP1A2 1685/4885MAPK1 3423/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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