Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 12/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | CCR5 | P51681 | 2/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2882795 | 0.85 | MCHR1 (0.44) | MCHR1KCNH2ACHEGSK3BDRD2 | |
| SCHEMBL2882793 | 0.85 | MCHR1 (0.44) | MCHR1KCNH2ACHEGSK3BDRD2 | |
| SCHEMBL12975700 | 0.81 | MCHR1 (0.51) | MCHR1KCNH2ACHEGSK3BDRD2 | |
| SCHEMBL2883696 | 0.76 | MCHR1 (0.52) | MCHR1KCNH2ACHEGSK3BDRD2 | |
| SCHEMBL2880435 | 0.75 | PRKAA2 (0.44) | MCHR1DRD2ADRA1ACCR5 | |
| SCHEMBL12975704 | 0.74 | MCHR1 (0.49) | MCHR1KCNH2DRD2ADRA1A | |
| SCHEMBL12975694 | 0.74 | ACHE (0.51) | MCHR1KCNH2ACHEDRD2ADRA1A | |
| SCHEMBL12975707 | 0.74 | MCHR1 (0.44) | MCHR1KCNH2ACHEGSK3BDRD2 | |
| SCHEMBL13664941 | 0.74 | MCHR1 (0.79) | MCHR1KCNH2ACHEGSK3B | |
| SCHEMBL19706633 | 0.73 | BRAF (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324049-A1 | DIARYL KETIMINE DERIVATIVE HAVING ANTAGONISM AGAINST MELANIN-CONCENTRATING HORMONE RECEPTOR | MSD K.K. (JP) | 2010-12-23 | — | — | US | disclosed |
| US-20100324049-A1 | DIARYL KETIMINE DERIVATIVE HAVING ANTAGONISM AGAINST MELANIN-CONCENTRATING HORMONE RECEPTOR | MSD K.K. (JP) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324049-A1 | DIARYL KETIMINE DERIVATIVE HAVING ANTAGONISM AGAINST MELANIN-CONCENTRATING HORMONE RECEPTOR | MC1R, MCHR1, MCHR2 | MCHR1 2/4885KCNH2 565/4885ACHE 3375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.