SCHEMBL129762

SCHEMBL129762

COc1c(C)cc(C)cc1C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.57
ALDH1A1 P00352 1/20 0.42
NR3C1 P04150 1/20 0.41
NR3C2 P08235 1/20 0.41
RAPGEF4 Q8WZA2 3/20 0.41
PTPN1 P18031 2/20 0.39
MAPT P10636 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
F2 P00734 1/20 0.36
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
PRSS3 P35030 1/20 0.36
CYP3A4 P08684 1/20 0.36
CA9 Q16790 1/20 0.36
LMNA P02545 1/20 0.36
TUBB4A P04350 1/20 0.35
TUBB P07437 1/20 0.35
TUBA3C P0DPH7 1/20 0.35
TUBA1B P68363 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16088857 0.85 PTPN1 (0.53) ACHEALDH1A1NR3C1NR3C2RAPGEF4
SCHEMBL13083360 0.84 ACHE (0.48) ACHEALDH1A1NR3C1NR3C2RAPGEF4
SCHEMBL10196604 0.84 ACHE (0.76) ACHEPTPN1MAPTL3MBTL1CYP3A4
SCHEMBL13256220 0.82 ACHE (0.46) ACHEALDH1A1RAPGEF4PTPN1MAPT
SCHEMBL258788 0.82 ACHE (0.46) ACHEALDH1A1NR3C1NR3C2RAPGEF4
SCHEMBL542689 0.82 ACHE (0.46) ACHEALDH1A1NR3C1NR3C2RAPGEF4
SCHEMBL359079 0.82 ALDH1A1 (0.48) ACHEALDH1A1NR3C1NR3C2PTPN1
SCHEMBL17662618 0.82 ACHE (0.46) ACHEALDH1A1NR3C1NR3C2RAPGEF4
SCHEMBL658125 0.82 PTPN1 (0.53) ACHEALDH1A1PTPN1MAPTTDP1
SCHEMBL31090180 0.82 PTPN1 (0.53) ACHEALDH1A1PTPN1MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 734 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11570909-B2 Flexible display apparatus and method of manufacturing the same BOE TECHNOLOGY GROUP CO., LTD. (CN) 2023-01-31 US claimed
US-8426115-B2 Patterning process and resist composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-04-23 US claimed
US-20110033803-A1 PATTERNING PROCESS AND RESIST COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-02-10 US claimed
US-20100159392-A1 PATTERNING PROCESS AND RESIST COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-06-24 US claimed
EP-1615867-A1 METHOD OF PURIFYING 2,6-XYLENOL AND METHOD OF PRODUCING POLY(ARYLENE ETHER) THEREFROM GENERAL ELECTRIC COMPANY (US) 2006-01-18 EP claimed
WO-2004094354-A1 METHOD OF PURIFYING 2,6-XYLENOL AND METHOD OF PRODUCING POLY(ARYLENE ETHER) THEREFROM GENERAL ELECTRIC COMPANY (US) 2004-11-04 WO claimed
US-20040211657-A1 METHOD OF PURIFYING 2,6-XYLENOL AND METHOD OF PRODUCING POLY(ARYLENE ETHER) THEREFROM GENERAL ELECTRIC COMPANY 2004-10-28 US claimed
EP-0983507-A1 TRICYCLIC TETRAHYDROQUINOLINE DERIVATIVES AND TRICYCLIC TETRAHYDROQUINOLINE COMBINATORIAL LIBRARIES Trega Biosciences, Inc. (US) 2000-03-08 EP claimed
WO-1998034111-A1 TRICYCLIC TETRAHYDROQUINOLINE DERIVATIVES AND TRICYCLIC TETRAHYDROQUINOLINE COMBINATORIAL LIBRARIES TREGA BIOSCIENCES, INC. (US) 1998-08-06 WO claimed
EP-0375937-B1 Improved method for removing volatile substances from polyphenylene ether or polyphenylene ether/styrene resin compositions GEN ELECTRIC (US) 1996-05-08 EP claimed
US-5204410-A Pellets, sheets form extrusion, vacuum venting, water injecting GENERAL ELECTRIC COMPANY (US) 1993-04-20 US claimed
US-5001214-A Low odor polyphenylene ether produced in the absence of odor causing amine, in presence of manganese chelate complex catalyst GENERAL ELECTRIC COMPANY (US) 1991-03-19 US claimed
US-4994217-A Blending with aromatic hydrocarbons, devolatilization GENERAL ELECTRIC COMPANY (US) 1991-02-19 US claimed
US-4992222-A Extruding resins in single pass through multiple stages of water injection and vacuum venting GENERAL ELECTRIC COMPANY (US) 1991-02-12 US claimed
EP-0381990-A1 Method for removing odor components from polyphenylene ether resins GENERAL ELECTRIC COMPANY (US) 1990-08-16 EP claimed
US-4942222-A REMOVES COMPONENTS SUCH AS DIHYDROBENZOFURAN DERIVATIVES TRIMETHYLANISOLE, 2,6-DIMETHYLCYCLOHEXANONE AND 2-ETHYLHEX-2-ENAL GENERAL ELECTRIC COMPANY (US) 1990-07-17 US claimed
EP-0375937-A2 Improved method for removing volatile substances from polyphenylene ether or polyphenylene ether/styrene resin compositions GENERAL ELECTRIC COMPANY (US) 1990-07-04 EP claimed
EP-0375968-A2 Improved method for preparing low odor polyphenylene ether resin GENERAL ELECTRIC COMPANY (US) 1990-07-04 EP claimed
US-4906700-A Method for preparing low odor polyphenylene ether resin including separating, distilling and recycling solvent GENERAL ELECTRIC COMPANY (US) 1990-03-06 US claimed
US-4707161-A Lightfastness of dyeings obtained with acid dyes or metal complex dyes on polyamides: treatment with copper hydroxamates BASF AKTIENGESELLSCHAFT (DE) 1987-11-17 US claimed