Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 6/20 | 0.42 |
| ▸ | ACHE | P22303 | 6/20 | 0.42 |
| ▸ | PREP | P48147 | 4/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.41 |
| ▸ | EP300 | Q09472 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | DRD1 | P21728 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16189647 | 0.89 | BCHE (0.52) | BCHEACHEPREPCYP1B1EP300 | |
| SCHEMBL128827 | 0.87 | CYP1B1 (0.40) | PTGS1PTGS2BCHEACHEPREP | |
| SCHEMBL127656 | 0.83 | ACHE (0.38) | BCHEACHEPREPCYP1B1EP300 | |
| SCHEMBL129785 | 0.79 | ACHE (0.43) | BCHEACHEPREPCYP1B1EP300 | |
| SCHEMBL128820 | 0.77 | TARBP2 (0.35) | PTGS1PTGS2BCHEACHEPREP | |
| SCHEMBL198012 | 0.76 | BCHE (0.49) | BCHEACHEPREPCYP1B1EP300 | |
| SCHEMBL10132426 | 0.75 | ALDH1A1 (0.50) | PTGS1PTGS2BCHEACHEALDH1A1 | |
| SCHEMBL10132417 | 0.74 | ALDH1A1 (0.49) | PTGS1PTGS2BCHEACHEALDH1A1 | |
| SCHEMBL10132415 | 0.74 | ALDH1A1 (0.54) | BCHEACHEPREPCYP1B1EP300 | |
| SCHEMBL10132362 | 0.74 | ALDH1A1 (0.51) | PTGS1PTGS2BCHEACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9227966-B2 | Antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-01-05 | — | — | US | disclosed |
| US-20140315939-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-10-23 | — | — | US | disclosed |
| US-20120059026-A1 | ANTIMICROBIAL AGENTS | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059026-A1 | ANTIMICROBIAL AGENTS | ZYX, Q6ZSR9, ZC3HAV1L | PTGS1 2524/4885PTGS2 2553/4885BCHE 2274/4885 |
| US-20140315939-A1 | ANTIMICROBIAL AGENTS | ZYX, Q6ZSR9, ZC3HAV1L | PTGS1 2892/4885PTGS2 2604/4885BCHE 2271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.