⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL852140 | 0.82 | — | — | |
| SCHEMBL852141 | 0.82 | — | — | |
| SCHEMBL852156 | 0.82 | — | — | |
| SCHEMBL12820958 | 0.82 | — | — | |
| SCHEMBL18404530 | 0.75 | — | — | |
| SCHEMBL11984277 | 0.75 | — | — | |
| SCHEMBL14985381 | 0.75 | ALDH1A1 (0.35) | — | |
| SCHEMBL10175234 | 0.75 | — | — | |
| SCHEMBL22271773 | 0.75 | ALDH1A1 (0.35) | — | |
| SCHEMBL13862108 | 0.73 | TDP1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022262686-A1 | KRAS G12D INHIBITORS | JINGRUI BIOPHARMA CO., LTD. (CN) | 2022-12-22 | — | — | WO | disclosed |
| EP-2252624-B1 | ELECTROLUMINESCENT METAL COMPLEXES WITH DIBENZO[F,H]QUINOXALINES | UDC IRELAND LTD (IE) | 2018-07-18 | — | — | EP | disclosed |
| WO-2013006738-A1 | COMPOUNDS FOR THE TREATMENT OF HIV | GILEAD SCIENCES, INC. (US) | 2013-01-10 | — | — | WO | disclosed |
| WO-2010138695-A1 | METHODS FOR TREATING NEUROFIBROMATOSIS | PTC THERAPEUTICS, INC. (US) | 2010-12-02 | — | — | WO | disclosed |
| EP-2053041-A2 | 1,3,5-Trisubstituted 2(1H)-pyridones as AMPA receptor inhibitors useful for the treatment of eg Parkinson's disease | Eisai R&D Management Co., Ltd. (JP) | 2009-04-29 | — | — | EP | disclosed |
| EP-1650284-B1 | Liquid crystal composition containing an optical active compound and liquid crystal electro-optical element | SEIMI CHEM KK (JP) | 2008-04-30 | — | — | EP | disclosed |
| EP-0974587-B1 | 1-SUBSTITUTED 4-CARBAMOYL-1,2,4-TRIAZOL-5-ONE DERIVATIVES AND HERBICIDE | HOKKO CHEM IND CO (JP) | 2008-04-23 | — | — | EP | disclosed |